Experimental Design and Data Analysis for Drug Pharmacokinetics and Pharmacodynamics

eagle-i ID

Resource Type

Properties

1. Fee for service

   Yes

2. Resource Description

   Experimental Design and Data Analysis offers users full access to the PhASR’s expertise in characterizing relationships between drug pharmacokinetics and pharmacodynamics, including specialized needs for sample collection, specimen preparation and storage, data analysis and statistical modeling. The service provides clinical and pre-clinical research expertise in understanding the expected kinetics and fate of a drug and/or its metabolites in a biological system. Through proper design of a pharmacokinetic sampling strategy, representative biological specimens are obtained before, during and after drug administration. Samples are processed and stored appropriately to ensure they remain representative of the biological samples originally obtained. For clinical studies, the PhASR works closely with the Clinical Treatment Unit to advise on sampling and storage strategies that will provide the highest quality data while considering patient needs and clinical procedures. After samples are analyzed, the PhASR completes appropriate analysis to ensure the quality of the raw data. The outcome of this service is a carefully designed PK/PD study, which yields data and results that achieve the investigator’s project objectives.

3. Contact

   The Pharmacoanalytical Shared Resource

4. Service Provided by

   The Pharmacoanalytical Shared Resource

5. Website(s)

   https://cancer.osu.edu/for-cancer-researchers/resources-for-cancer-researchers/shared-resources/pharmacoanalytical/services-and-fees

6. Part of Collection

   The Ohio State University Comprehensive Cancer Center Collection