Thermo Scientific Q Exactive Ultra-High Mass Range (UHMR) Hybrid Quadrupole-Orbitrap mass spectrometer

eagle-i ID

Resource Type

Properties

1. Related grant number

   1P41GM128577-01

2. Resource Description

   The Thermo Scientific Q Exactive Ultra-High Mass Range (UHMR) Hybrid Quadrupole-Orbitrap instrument which enables analysis of extra-large molecules (m/z 350-80,000) with high mass accuracy. The UHMR is equipped with a higher-energy collision-induced dissociation (HCD) cell capable of acceleration voltages up to 300 V, as well as in-source trapping capabilities for improved declustering of ions. The Wysocki lab has two of these instruments and they are both modified with custom surface-induced dissociation (SID) devices. The UHMRs are primarily used for analysis of proteins and protein complexes by both direct infusion and online non-denaturing separation techniques. One instrument was purchased with funds from P41GM128577 and the other is part of a direct collaboration with Thermo Scientific.

3. Contact

   Laura VanArsdale

4. Website(s)

   https://nativems.osu.edu/

5. Funded by

   NIH National Institute of General Medical Sciences

6. Part of Collection

   Campus Chemical Instrument Center

7. Part of Collection

   Dr. Vicki Wysocki Ohio Eminent Scholar Collection

8. Location

   Resource for Native Mass Spectrometry Guided Structural Biology (NIH P41)