Thermo Scientific Q Exactive Ultra-High Mass Range (UHMR) Hybrid Quadrupole-Orbitrap mass spectrometer
eagle-i ID
http://eagle-i.rf.ohio-state.edu/i/00000176-e28b-e377-28ff-947680000000
Resource Type
Properties
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Related grant number
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1P41GM128577-01
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Resource Description
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The Thermo Scientific Q Exactive Ultra-High Mass Range (UHMR) Hybrid Quadrupole-Orbitrap instrument which enables analysis of extra-large molecules (m/z 350-80,000) with high mass accuracy. The UHMR is equipped with a higher-energy collision-induced dissociation (HCD) cell capable of acceleration voltages up to 300 V, as well as in-source trapping capabilities for improved declustering of ions. The Wysocki lab has two of these instruments and they are both modified with custom surface-induced dissociation (SID) devices. The UHMRs are primarily used for analysis of proteins and protein complexes by both direct infusion and online non-denaturing separation techniques. One instrument was purchased with funds from P41GM128577 and the other is part of a direct collaboration with Thermo Scientific.
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Contact
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Laura VanArsdale
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Website(s)
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https://nativems.osu.edu/
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Funded by
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NIH National Institute of General Medical Sciences
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Part of Collection
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Campus Chemical Instrument Center
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Location
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Resource for Native Mass Spectrometry Guided Structural Biology (NIH P41)
