Thermo Scientific Q Exactive Ultra-High Mass Range (UHMR) Hybrid Quadrupole-Orbitrap mass spectrometer

eagle-i ID

Resource Type

Properties

1. Related grant number

   1P41GM128577-01

2. Resource Description

   The Thermo Scientific Q Exactive Ultra-High Mass Range (UHMR) Hybrid Quadrupole-Orbitrap instrument which enables analysis of extra-large molecules (m/z 350-80,000) with high mass accuracy. The UHMR is equipped with a higher-energy collision-induced dissociation (HCD) cell capable of acceleration voltages up to 300 V, as well as in-source trapping capabilities for improved declustering of ions. The Wysocki lab has two of these instruments and they are both modified with custom surface-induced dissociation (SID) devices. The UHMRs are primarily used for analysis of proteins and protein complexes by both direct infusion and online non-denaturing separation techniques. One instrument was purchased with funds from P41GM128577 and the other is part of a direct collaboration with Thermo Scientific.

3. Contact

   Laura VanArsdale

4. Website(s)

   https://nativems.osu.edu/

5. Funded by

   NIH National Institute of General Medical Sciences

6. Part of Collection

   Campus Chemical Instrument Center

7. Location

   Resource for Native Mass Spectrometry Guided Structural Biology (NIH P41)