The Mass Spectrometry and Proteomics Facility (MS&P) or Proteomics Shared Resource (PSR) as it is known within the OSUCCC, provides investigators access to advanced mass spectrometry instrumentation and analysis for protein identification, characterization, and quantification. Using a variety of analytical platforms, researchers are able to discover novel differentially expressed proteins in serum, urine, BAL fluid, saliva, frozen tissues, formalin-fixed tissues and cell lysates. The MS&P/PSR is part of the Campus Chemical Instrument Center managed by the OSU Office of Research, with significant operational management by the OSUCCC. The MS&P/PSR is located within OSUCCC space in the Biomedical Research Tower. This facility is an interdisciplinary unit that provides researchers with technical expertise and state-of-the-art instrumentation needed to identify proteins, protein modifications, protein interactions and protein biomarkers as well as protein quantitation studies in cancer samples. The MS&P/PSR can identify proteins from solution, 1D and 2D gels using electrophoresis and imaging equipment, robotic sample handlers and (tandem) mass spectrometers.