The Leukemia Tissue Bank Shared Resource (LTBSR) helps scientists translate basic research to the clinical setting by providing central collection, processing and storage of tissue samples from patients with leukemia, myeloma or lymphoma enrolled on Ohio State University Comprehensive Cancer Center – James Cancer Hospital and Solove Research Institute (OSUCCC – James) protocols. These samples are available to investigators at Ohio State and to outside collaborators who study the cellular and molecular properties of these diseases. The ability to examine tumor cells from patients is an essential part of determining the causes of cancer and developing new and effective treatments.
A National Cancer Institute (NCI)-sponsored biorepository, the LTBSR has more than 40,000 vials of cryopreserved viable cells and 13,000 vials of matched frozen plasma and/or serum samples from more than 4,000 patients treated for leukemia and other malignancies.
Apheresis samples obtained from patients with hematologic disease who undergo a leukapheresis procedure.
Biopsies obtained for research as part of a normal removal during patient treatment/surgery.
Leukocytes obtained from bone marrow aspirates of patients with hematologic diseases.
Cord blood obtained from birthing procedure to distribute to researchers as healthy, normal control.
Hip bone tissue acquired post surgery for hip replacements to distribute to researchers as healthy, normal control.
Human plasma obtained from bone marrow and peripheral blood samples from patients with hematologic diseases.
Human serum obtained from peripheral blood samples from patients with hematologic diseases.
Lymph nodes of patients with hematologic diseases.
Leukocytes obtained from peripheral blood of patients with hematologic diseases.
Skin punch biopsy obtained from patients with hematologic diseases.
BioMS is an Alliance cooperative group database used for sample shipping and tracking of specimens under Alliance clinical trials (non-OSU).
ELIMS is an online database built by Nathan Poeppleman allowing for web based inventory management of patient samples and inventory.
Excel used for local tracking of samples obtained from patients.
OpenSpeciment is an Alliance cooperative group database used for sample shipping and tracking of specimens under Alliance clinical trials (non-OSU).
Samples obtained from patients with COVID-19. Samples are processed and stored locally under the most critical safety procedures.
Samples obtained from patients with EBV.
Samples obtained from patients with Hepatitis A, B or C.
Samples obtained from patients with HIV.
OSU LTB research collection protocol - OSU-1997C0194. Protocol used to consent patients and obtain extra material based on their current treatment regiment (will not ask for additional outside of already drawn material).
Lab uses many reagents in processing samples.
The OSUCCC – James Shared Resources and core facilities provide specialized services to cancer researchers. They offer cost-effective, state-of-the-art technology and instrumentation; expert guidance and training; and clinical, administrative and technical support.
Collection of samples from consented patients.
Data management of all samples in the tissue bank
Sample distribution done through lab manager (Chris Manring) and director. Samples distributed equally based on the parameters of the researcher.