The Biomedical Informatics Shared Resource (BISR) analyzes high-throughput, high dimensional biological data and other biomedical data and information using state-of-the-art informatics tools and high-quality informatics analysis for OSUCCC – James investigators.
The BISR has two service arms: Computational Biology Services and Data Sharing Infrastructure.
BISR offers computational biology and bioinformatics consultative services that include:
Analysis of next generation sequencing data including Exome-sequencing, RNA-sequencing, ChIP-sequencing and whole genome re-sequencing
Analysis of microarray datasets, including mRNA (Affymetrix), SNP, and micro-RNA
Analysis of nCounter NanoString data
Analysis of publicly available datasets using search parameters defined by the OSUCCC client—for example, from the Gene Expression Omnibus (GEO) database of microarray results, The Cancer Genome Atlas (TCGA) and the International Cancer Genome Consortium (ICGC) data portals that allows access to results of thousands of deep sequencing projects
Pathway analysis of results from microarray and sequencing data
Image analysis, including the processing of images in order to reconstruct a three-dimensional tissue, or improvement of image quality using specialized computer programs