The Solid Tumor Translational Science Shared Resource (STTSSR) team works closely with clinical and translational scientists to develop a customizable portfolio of biomarker assays in order to provide innovative, correlative science studies associated with early-phase solid tumor oncology clinical trials. This resource works closely with clinical investigators in the design and management of studies and provides guidance related to assay development and analysis. The STTSSR serves as a central repository for specimens collected from patients on trials and is responsible for processing the tissue for any number of downstream analyses. In addition to developing novel assays, i the STTS-SR partners with other OSUCCC Shared Resources to utilize available technologies such as next-generation sequencing, RNA expression analysis and proteomics. In these situations, the STTSSR is responsible for obtaining and preparing the patient samples for downstream analyses and then collects and organizes the data.
The STTSSR resource also helps identify and develop partnerships among investigators and pharmaceutical companies to gain access to new drugs and compounds and to provide corresponding correlative testing and analyses for cancer studies.