The Cancer Diagnosis Program of the National Cancer Institute (NCI) initiated the Cooperative (AKA Collaborative) Human Tissue Network (CHTN) grant in 1987. The Ohio State University was an original NCI grantee for this program and 2019 was our 33rd year of CHTN funding. The major goal of the Cooperative Human Tissue Network is to facilitate the use of human tissues in biomedical research for basic and applied scientists from academia, industry and government to accelerate the advancement of scientific discoveries, as well as progress in cancer diagnosis and treatment. The Cooperative Human Tissue Network uses a prospective biospecimen procurement model rather than a biobanking model and works directly with investigators to determine the appropriate tissue sources (e.g. surgery, autopsy and transplant) in order to tailor tissue-processing methods to meet the research needs of the specific investigator. The Cooperative Human Tissue Network obtains human tissues and fluids from remnant materials removed from medically indicated surgical resections, autopsies and other procedures. The Tissue Procurement Service (TPS) is a supporting service of the Cooperative Human Tissue Network.
Because the CHTN is an NCI supported resource, investigators are only charged a LOW processing fee for each sample to offset the costs of collecting, handling and preparing the specimens in accordance with the detailed requirements of the investigator. A sample is defined as one processed piece of a specimen, regardless of the sample size or type of processing. Each investigator is also responsible for all shipping costs.