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Campus Chemical Instrument Center (CCIC) Mass Spectrometry and Proteomics

Summary:

The mandate of the CCIC Mass Spectrometry and Proteomics (MSP) Facility is to provide state-of-the-art instrumentation and personnel expertise for a wide variety of research projects. Main areas of services we provide include i) proteomics, ii) metabolomics, and iii) general mass spec analyses for research groups. We also participate and provide support for grant applications and education. The Mass Spectrometry and Proteomics Facility at CCIC is an interdisciplinary unit, servicing faculty from the colleges of Biological Sciences, Education and Human Ecology, Engineering, Food, Agriculture & Environmental Sciences, Mathematical and Physical Sciences, Medicine, Optometry, Pharmacy, and Veterinary Medicine just to name a few. CCIC also serves scientists from other universities and industry within and outside of Ohio.

If you do not know what kind of service you need, please contact Dr Arpad Somogyi. Submit a Service Request Form through FOM – see instructions via link below. Please provide as much information as possible regarding the sample and desired analysis. Please note any special sample instructions or analysis instructions on the form. The more information we have, the better the results and the faster we can return data.

Bring sample(s) and the Service Request Form between 8AM & 5PM or mail to:

OSU Mass Spectrometry & Proteomics Facility
460 W 12th Ave, Rm 250 Biomedical Research Tower (BRT)
Columbus, OH 43210
Phone: 614-247-8789
Fax: 614-292-5955

Bring your Buck ID for access to our Facility in the Biomedical Research Tower.

Results are emailed and all data is electronic.
Samples are discarded after analysis, so please indicate if you would like to pick up any unused sample.

Affiliations:

People:

    Resources:

    Instruments

    • Agilent 6545 Quadrupole Time of Flight LC-MS system ( Mass spectrometer )

      Agilent 6545 Quadrupole Time of Flight LC-MS system The Agilent 6545 QTOF is equipped with two Agilent 1290 UHPLC systems, one for reverse
      phase and one for normal phase separations. This instrument is designed for high resolution and broad profiling of unknown compounds in untargeted metabolomics studies. The extended TOF flight tube and SWARM auto-tuning allows for both high sensitivity and dynamic range, offering ideal specifications for complex sample analysis.

    • Bruker 15 Tesla FT-ICR mass spectrometer ( Mass spectrometer )

      "Ultrahigh resolution (>1,000,000) and mass accuracy (< 1 ppm). Equipped with a dual ionization source (MALDI and ESI). ETD and ECD options available. Used mostly for untargeted metabolomics, small molecule MALDI imaging, and top down proteomics"
      https://www.ccic.osu.edu/MSP-Acknowledging

    • Bruker amaZon ETD ( Ion trap mass spectrometer )

      Bruker amaZon ETD Ultra performance, high sensitive proteomics ion trap with dual funnel ion guide and advanced ETD / PTR capabilities (Electron Transfer Dissociation and Proton Transfer Reaction).

    • Bruker timsTOF Pro HPLC-MS/MS with Ion Mobility ( Time-of-flight secondary ion mass spectrometer )

      Bruker timsTOF Pro HPLC-MS/MS with Ion Mobility High resolution TOF analysis/sequencing of peptides separated by trapped ion mobility prior MS/MS fragmentation. The instrument has high duty cycle (almost 100%) and high sensitivity (200-250 ng of proteins). Large numbers of proteins can be identified in complex protein mixtures containing 5,000+ proteins. Material Separation Instrument. Time-of-flight secondary ion mass spectrometer.

    • Bruker ultrafleXtreme MALDI-TOF-TOF MS ( MALDI-TOF mass spectrometer )

      Bruker ultrafleXtreme MALDI-TOF-TOF MS. The Bruker-Daltonics UltrafleXtreme MALDI-TOF-TOF MS-Tissue Imaging Platform with collision- induced dissociation (CID) capabilities for structural determination by MALDI.

    • Thermo Orbitrap Fusion HPLC-MS/MS System ( Tandem mass spectrometer )

      Ultrahigh resolution and excellent mass accuracy. Used mostly for bottom-up proteomics.

    • Thermo Scientific LTQ Orbitrap ( Tandem mass spectrometer )

      Thermo Scientific LTQ Orbitrap. A LTQ Orbitrap XL exclusively used for advanced proteomic projects that require high resolution and high mass accuracy. This instrument is a unique hybrid mass spectrometer that combines a linear ion trap and an orbitrap mass analyzer.

    • Thermo Scientific QE Plus (Metabolomics, QE-M) ( Tandem mass spectrometer )

      Thermo Scientific QE Plus (Proteomics, QE-P) Ultrahigh resolution and excellent mass accuracy. Used almost exclusively for bottom-up proteomics.

    • Thermo Scientific QE Plus (Proteomics, QE-P) ( Tandem mass spectrometer )

      Thermo Scientific QE Plus (Proteomics, QE-P) Ultrahigh resolution and excellent mass accuracy. Used almost exclusively for bottom-up proteomics.

    • Therrmo Quantiva Triple Quadrupole HPLC MS/MS System ( Tandem mass spectrometer )

      Thermo Quantiva Triple Quadrupole HPLC MS/MS System Ultrahigh sensitivity, used mostly for quantitative (targeted) metabolomics.

    Resource Collection


    Web Links:

    Last updated: 2021-02-10T12:23:51.418-05:00

    Copyright © 2016 by the President and Fellows of Harvard College
    The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016