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Flavor Research and Education Center


The Flavor Research and Education Center (FREC) works to understand drivers of flavor perception and, ultimately, food choice. We have built a holistic analytical platform that combines our extensive expertise with modern and advanced instrumentation to investigate and address unique and challenging aspects of flavor discovery.

Our services include chemical profiling of non-volatile and volatile compounds in different food matrixes, quantification of aroma and flavor compounds, identification of off-flavors, activity-guided isolation of key bioactive compounds, characterization of flavor interactions—including the discovery of flavor modulating compounds, and sensory analysis as part of analytical projects.





    • Gas Chromatography-Mass Spectrometry platform (GC/MS platform) ( Gas chromatography-mass spectrometry platform )

      Our center has a vast background in volatile and aroma compound analysis by GC and GC-O instrumentation. Our platform offers high selectivity, specificity, and sensitivity, even for samples with low-abundant compounds.

      • Gas chromatography-mass spectrometry (with and without olfactometry): single quadrupole, triple quadrupole, and quadrupole-time of flight (Q-ToF), mass spectrometers for quantification and structural elucidation.

      • Gerstel Rail multifunctional autosamplers and sample preparation robot for GC and GC/MS. The MultiPurpose Sampler (MPS) provides modern analytical laboratories high throughput, high performance, and unparalleled flexibility.

      GC/MS QqQ Agilent 7010B
      GC/MS QToF Agilent 7250
      GC/MS SQ Agilent 5977

    • LC-Preparative platform ( Liquid chromatography mass spectrometry platform )

      Multiple prep-LC instrumentation together with customized fractionation methods enable fast and reproducible multi-dimensional liquid chromatography for the isolation and purification of taste active and flavor modulating compounds needed for identification (NMR) and quantification.

      • Liquid chromatography/mass spectrometry (LC/MS): single quadrupole and triple quadrupole mass spectrometers for chromatographic isolation and identification.

      Prep LC/MS-TQD Waters
      Prep LC/MS-QuattroMicro API Waters
      Prep LC/MS-Micromass ZQ Waters
      Semi Prep LC/MS QuattroMicro Waters

    • UPLC/MS platform ( Liquid chromatography mass spectrometry platform )

      Our modern LC-MS platform delivers accurate analysis with high reproducibility. Our LC systems coupled with the most advanced MS detectors provide high-quality analysis, separation, and compound identification for all types of food samples.
      Liquid chromatography/mass spectrometry (LC/MS): triple quadrupole, and quadrupole-time of flight (Q-ToF), mass spectrometers for quantification, and structural elucidation. High-quality sample preparation with Hamilton automated robot to increase throughput and enhancing laboratory efficiencies.
      UPLC/MS-QToF Agilent 6546
      UPLC/MS-QToF Agilent 6545
      UPLC/MS-TQ-XS Xevo Waters
      UPLC/MS-TQ-S Xevo Waters
      UPLC/MS-QToF Xevo G2 Waters
      Hamilton Microlab® Star Automation Robot

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    Last updated: 2020-10-02T11:08:33.435-04:00

    Copyright © 2016 by the President and Fellows of Harvard College
    The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016