The Veterinary Biospecimen Repository collects both tumor and normal (whole blood, tissue, serum, plasma, urine) samples following guidelines modeled after the Children’s Oncology Group tissue banking protocols and serves as a valuable resource of spontaneous tumors in the pet population with the goal of characterizing these tumors to provide a framework for evaluation of novel therapeutic approaches in animals and humans. The VCRS is a unique shared resource enabling the integration of multiple models of cancer into the process of drug development and translational therapeutics.
Member:
Holly Borghese
flash frozen , OCT blocks, and FFPE blocks from naturally occurring tumors in client-owned dogs who are patients at the VMC.
flash frozen , OCT blocks, and FFPE blocks from naturally occurring tumors in client-owned cats who are patients at the VMC
Flash frozen , OCT blocks, and FFPE blocks from normal tissue collected from animals at the same time the tumor samples are collected.
Plasma processed from blood collected the day of surgery or euthanasia and tumor collection.
serum processed from blood collected the day of surgery or euthanasia and tumor collection.
Whole blood collected the day of surgery or euthanasia and tumor collection.
stage, grade, treatment data
A redacted copy of the pathology report from the veterinary pathologists at Ohio State.
age, sex, breed.
Tumor site, size, whether it received treatment prior to collection.
This SOP outlines each step in collection, sample data recording, processing and storage of all samples in the repository
Clinical trials in client-owned animals in partnership with other academic disciplines, academic institutions, nonprofits, and pharma, biotech, nutrition industries. Pre-phase-one clinical trials for potential therapies for human medicine.
The OSUCCC – James Shared Resources and core facilities provide specialized services to cancer researchers. They offer cost-effective, state-of-the-art technology and instrumentation; expert guidance and training; and clinical, administrative and technical support.
Assistance with all aspects of carrying out a veterinary clinical trial: patient scheduling, data entry, treatment administration by licensed RVT's
Assistance in formulating a clinical trial budget; congruency review with protocol and consent forms to make sure all costs are captured.
Management of clinical trial fund expenditures, client billing adjustments.
Marketing of open clinical trials on social media, website, at public events, and via regular emails to referring clinicians.
Creation and storage of data instruments for clinical trials