Post-Translational Modification Analyses
eagle-i ID
http://eagle-i.rf.ohio-state.edu/i/00000176-2ea4-1f80-ff38-acfe80000000
Resource Type
Properties
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Fee for service
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Yes
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Resource Description
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Post-Translational Modification Analyses: Post-translational modification (PTM) is the chemical modification of a protein after translation. These modifications induce a shift in mass, therefore can be identified using mass spectrometry. Common PTM analysis includes phosphorylation, methylation, acetylation and oxidation. Samples may be enriched prior to digestion and then analyzed on the ultra-high-resolution Orbitrap Fusion or timsTOF PRO using LC-MS/MS to determine the sequence of the peptide and the location of the modification. The PSR has extensive experience working with researchers to identify and characterize customized post-translational modifications, amino acid mutations and peptide crosslinks.
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Service Fee URL
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https://www.ccic.osu.edu/MSP-Rates
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Contact
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Liwen Zhang
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Service Provided by
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The CCC Proteomics Shared Resource (PSR)
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Website(s)
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https://cancer.osu.edu/for-cancer-researchers/resources-for-cancer-researchers/shared-resources/proteomics
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Website(s)
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https://www.ccic.osu.edu/msp
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Part of Collection
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Campus Chemical Instrument Center
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Part of Collection
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The Ohio State University Comprehensive Cancer Center Collection
