eagle-i The Ohio State UniversityThe Ohio State University

Post-Translational Modification Analyses

eagle-i ID


Resource Type

  1. Material analysis service


  1. Fee for service
  2. Resource Description
    Post-Translational Modification Analyses: Post-translational modification (PTM) is the chemical modification of a protein after translation. These modifications induce a shift in mass, therefore can be identified using mass spectrometry. Common PTM analysis includes phosphorylation, methylation, acetylation and oxidation. Samples may be enriched prior to digestion and then analyzed on the ultra-high-resolution Orbitrap Fusion or timsTOF PRO using LC-MS/MS to determine the sequence of the peptide and the location of the modification. The PSR has extensive experience working with researchers to identify and characterize customized post-translational modifications, amino acid mutations and peptide crosslinks.
  3. Service Fee URL
  4. Contact
    Liwen Zhang
  5. Service Provided by
    The CCC Proteomics Shared Resource (PSR)
  6. Website(s)
  7. Website(s)
  8. Part of Collection
    Campus Chemical Instrument Center
  9. Part of Collection
    The Ohio State University Comprehensive Cancer Center Collection
  10. Part of Collection
    Dr. Vicki Wysocki Ohio Eminent Scholar Collection
Provenance Metadata About This Resource Record

    Copyright © 2016 by the President and Fellows of Harvard College
    The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016