This is a summary list of all resource providers at The Ohio State University . The list includes links to more detailed information, which may also be found using the eagle-i search app.
The mission of The Advanced Computing Center for the Arts and Design (ACCAD) is to educate, inform, and inspire innovative thinking and experimentation in the area of arts and technology through collaborative academic and research experiences for graduate students and faculty.
The research conducted in the Aeronautical and Astronautical Research Laboratories (AARL) extends from the very fundamental to the applied, from the very small laboratory scale to full application scale, and covers a wide variety of aerospace applications. AARL is located adjacent to The Ohio State University’s Don Scott Airport, and encompasses two additional laboratories: the Gas Dynamics and Turbulence Laboratory (GDTL) and the Gas Turbine Laboratory (GTL). AARL has been a major center of aerospace research and graduate education and has been the site of many innovative research activities and centers including NASA’s General Aviation Airfoil Design and Analysis Center in the 1970s, NASA’s Hypersonic Research and Training Center in the 1990s, and the Air Force’s Collaborative Center of Control Science in the 2000s.
The new Aerospace Research Center (ARC) will focus The Ohio State University’s aerospace activities to optimize and connect core strengths and to address current and future air transportation challenges.
ARC is a unique concept among U.S. academic institutions. Adopting an industry model, the center unites many aerospace disciplines, including power and propulsion, aerodynamics, material science, control and manufacturing, all under one virtual roof.
The Analytical Cytometry Shared Resource (ACSR) provides state-of-the-art flow cytometry analysis and sorting of cell populations using selected cellular markers. Flow cytometry is a critical technology for cancer research, and the ACSR is used extensively by all scientific programs in the OSUCCC – James and by the broader Ohio State research community.
The Analytical Spectroscopy Laboratory provides centralized care of, and training on, a variety of instruments. Researchers may have access to instruments which are not available in their own labs because they are expensive or used infrequently. New ideas can be tested. Results and publications generated from ASL instruments can be used to justify proposals for instruments for a Principal Investigator's own laboratory.
The Lab Manager trains the users how to operate the instruments, and is available for advice on how to get the best results out of the measurements. Users who are certified have around the clock access.
The 4.7T/40cm MRI Facility was created as part of the Ohio Cellular and Molecular Imaging Consortium (OCMIC) with the goal to advance state of the art technology for animal imaging at the molecular, cellular and system level, to serve as a resource for medical research, biotechnology advances and pharmaceutical development, and for probing in vivo gene function, disease processes and therapeutic applications including drug delivery and trials. The goal of the Consortium is to facilitate inter-institutional collaboration between Academic Institutions in Ohio and technology transfer to Industry.
Applied pathology services include post mortem examinations performed on cases from the Ohio State University Veterinary Medical Center and on cases from referring veterinarians, a biopsy service limited to cases from the Veterinary Medical Center and a library which is responsible for distributing results, keeping records and microslides on autopsy and biopsy cases, and providing pathology teaching materials to faculty and students.
The ABRC collects, preserves, reproduces and distributes diverse seed and other stocks of Arabidopsis thaliana and related species. Resources are donated by researchers from around the world. More than 100,000 samples are shipped annually to researchers and educators from 60 countries.
ABRC holdings include:
Arabidopsis seed stocks and clones
Arabidopsis cell lines and protein chips
Seed and clone resources from related species
Cloning vectors and host strains
The Behavioral Measurement Shared Resource (BMSR) assists investigators who wish to incorporate behavioral research into the broader research goals of the OSUCCC – James. The BMSR provides expertise and training to support the needs of prevention, cancer control, and clinical researchers in their pursuit of behavioral research investigation and methods.
Atomic Force Microscopy (AFM) is a high-resolution microscopy technique that produces precise topographic images of a sample by scanning the surface with a nanometer-scale probe called cantilever. One of the advantages of AFM imaging is that it enables imaging in air or liquid environment with minimal sample preparation. In the biomedical field, AFM is used to visualize single biomolecules, live or fixed cells or tissues at nanoscale resolution without drying or coating them.
Besides imaging, AFM has been widely used in mechanobiology. It can measure force from ~10 pN up to μN (limited by the spring constant of the cantilever), which is suitable for a wide range of applications, from single biomolecule study, protein-protein/DNA interaction, to cell-cell and cell-tissue interaction.
When coupled with a fluorescence microscope, the investigator can monitor intracellular dynamics while using AFM to apply precisely controlled force at desired location of the sample. This is particularly useful for the mechano-transduction study.
The latest tool for AFM in biological applications, the Bioscope II with Nanoscope V controller (Digital Instruments, Santa Barbara, CA), is available in the Bio-AFM core. The state-of-the-art instrument is coupled to an inverted Zeiss fluorescence microscope, which enables the user to perform simultaneous AFM and light/fluorescence microscopy on biological samples.
We also have a brand new JPK ForceRobot 300, which is specifically designed for high-volume automatic force measurement, for example nano-indentation and biomolecule force measurement.
We train and assist users in use of AFM for their research, consult and advise users on experimental design, offer equipment time or perform AFM experiments and related data analysis for them.
This core was formed in 2002 to focus the department's investments in shared-use infrastructure. The goals of the core are to provide and maintain selected instrumentation and to provide sufficient training to facilitate end-user operation.
This area contains approximately 3,000 square feet dedicated to the latest state-of-the art, cutting edge technology motion capture and neuromuscular control assessment. The lab utilizes an inter-disciplinary team of experts to investigate rehabilitation approaches on a wide variety of musculoskeletal diseases, evaluating orthopaedic implants and surgical techniques, and evaluating sports capabilities.
The Biological Sciences Greenhouse Facility supports undergraduate, graduate and faculty research in the areas of population ecology, systematics and evolutionary biology, genetics and biotechnology, physiology and toxicology, medical entomology, molecular biology, integrated pest management and biological control.
The facility offers a variety of plant growth spaces to meet the needs of our researchers. The facility has individually computer controlled greenhouse rooms in three sizes: large 24' X 40', medium 24' X 20', and small 10' X 12'. Researchers may request remote access to monitor greenhouse conditions through the environmental control system.
The Biomedical Informatics Shared Resource (BISR) supports advanced biological and biomedical research conducted by OSU researchers by facilitating high-throughput, novel experiments that link multidimensional phenotypic and biomolecular data sets.
BISR utilizes and coordinates data-intensive computational methods for all high throughput data analysis, as well as pathway and network analysis. BISR also assists researchers with accessing publicly available data to generate new hypotheses and draw new conclusions via integrative analysis of both public and private data sources. BISR fosters collaborations with OSU researchers; customizes analysis workflows to meet the unique needs of their projects, interprets and presents results, works on manuscript preparation and design and planning of grant applications.
Instrumentation in the facility in includes circular dichroism, fluorescence techniques, titration, etc. for the needs of a biological researcher.
The broad mission of the OSUCCC Biospecimen Services Shared Resource (BSSR) is to support cutting edge translational research to advance the prevention, diagnosis and treatment of cancer.
The education and outreach programs of the Byrd Polar and Climate Research Center focus on conveying the cutting-edge science of the Center’s research teams, improving geosciences education, and providing educational opportunities and technical expertise on climate change. Of special note over the past two years, the outreach team has received funding for two NSF-funded projects, begun work on a climate action plan for the City of Columbus, created extensive collaborations with the reinvigorated State Climate Office of Ohio, and built a bridge to the agricultural community through work with OSU Extension.
The Byrd Center maintains a machine shop equipped to fabricate ice core drills, sediment drills, and any other pieces of equipment required by the Center’s Principal Investigators and their students and postdocs. Paul Green serves as the Center’s design engineer and is responsible for all fabrication activities. The shop houses a CNC mill (photo), a manual mill, a metal lathe (photo), a brake box, a metal shear, a band saw, and a panel saw all of which allow Paul to work with wood, metals, and plastics. In addition to maintaining and operating the equipment, Paul works with the Center’s PIs to design solutions to meet their scientific, field, and instrumental requirements.
Named in honor of one of America's most famous explorers, the Byrd Polar and Climate Research Center of The Ohio State University is recognized internationally as a leader in polar and alpine research. The Center's research programs are conducted throughout the world.
Research at the Center focuses on the role of cold regions in the global climate system, with major themes focused on:
Climatic reconstruction of glacial and post-glacial times;
polar ice-sheets: dynamics, history and ice-atmosphere interactions; high-latitude landform evolution, soils and hydrology;
geologic evolution of Antarctica; investigations of ocean dynamics and environmental-chemical processes; and the history of polar exploration.
To see all the resources that fall under Byrd Polar and its sub-areas please click the Byrd Polar and Climate Research Center Collection link at the bottom of the page.
Collaboration with a biostatistician typically provides higher quality and reliable results that stand up to critical peer review. Issues that are not obvious to investigators are identified and addressed and all efforts are made to ensure the investigator’s aims are met through statistically rigorous methods.
Biostatisticians vary in their area of expertise. Some focus on clinical trial design, analysis and oversight, others focus on observational study methods, laboratory experimental design and analysis, or high dimensional studies (microarray, sequence data, etc.). Specific biostatistical expertise is also important to peer reviewers.
The Ohio State University Center for Clinical and Translational Science (CCTS) is a collaboration among The Ohio State University, The Ohio State University Wexner Medical Center and Nationwide Children's Hospital dedicated to turning the scientific discoveries of today into life-changing disease prevention strategies and the health diagnostics and treatments of tomorrow.
Funded by a multi-year Clinical and Translational Science Award from the National Institutes of Health, the CCTS leverages expertise from every college across the University, including scientists and clinicians from the seven Health Science Colleges, the College of Engineering, OSU Wexner Medical Center and Nationwide Children’s Hospital, community health and education agencies, business partnerships and regional institutional network partnerships.
The CCTS provides financial, organizational, and educational support to biomedical researchers, as well as opportunities for community members to participate in credible and valuable research. In addition, the CCTS provides research consultation services designed to help faculty, staff and service providers manage their translational research projects.
The goal of the NIH CTSA program is to enhance the translation of basic science discovery to improve human health by enabling researchers to work in unprecedented ways to advance medical research.
To be eligible for participation in our programs and services, one must become a CCTS Member. Not only do members have full access to our programs, but they also are the first to receive exciting news about upcoming funding cycles, new voucher programs, educational events, and more through our monthly online newsletter, The CCTS Investigator. go.osu.edu/cctsmember.
This page shows resources available at the top level of CCTS. To see all resources that fall under CCTS and its sub-programs navigate to the CCTS collection: https://search.eagle-i.net/central/#inst?uri=http://eagle-i.rf.ohio-state.edu/i/00000174-9d14-5e1e-b8fb-15ae80000000
The Clinical Research Center (CRC) is a 13-bed research unit located on the 2nd floor of the Davis Medical Clinic in the Wexner Medical Center at The Ohio State University. The Center is funded as part of the OSU Center for Clinical and Translational Science (CCTS) through a Clinical and Translational Science Award (CTSA) grant from the National Institutes of Health (NIH).
The research unit can facilitate both inpatient and outpatient studies in areas such as: AIDS, autism, cardiology, diabetes, , lupus, neuromuscular diseases, nursing, nutrition, obstetrics and gynecology, pediatrics, psychology, and stress and immunity. Research areas located on the unit include a room for smoking studies, a pediatric room, exercise physiology and metabolic measurement equipment, and a specimen processing laboratory. In addition to the main nursing unit services are also available from the Bionutrition Laboratory and the Analytical & Development Laboratory.
Available nursing services include: Administering study medication, bronchoscopy assistance, DXA, EKG, phlebotomy, PKs or frequent blood sampling, questionnaire administration, telemetry, scatter nurse, specimen processing and short-term freezer storage, and teaching. Additional services may be requested as needed.
Available bionutrition services include: Expertise in diet design and diet analysis, body composition and indirect calorimetry assessments, and education and counseling services. The on-site metabolic kitchen provides regular, specialized, or nutrient controlled meals for research participants according to study specifications. Additional services may be developed as needed.
Available laboratory services include: Sample processing, assay implementation, and sample storage in monitored freezers for human as well as animal samples. New assays may be developed for investigators as needed.
• Educational Opportunities to help research team members learn the most effective ways to identify, engage with, and incorporate valuable feedback from their stakeholders.
• Connect and Engage with collaborative research partners across OSU and NCH, and with local, regional, and statewide community partners and organizations (including Central Ohio, Southeastern Ohio/Appalachia, and OSU Extension offices across the state).
• Cultural Competency and Dissemination opportunities to connect with stakeholders via Science Cafés & Community Advisory Boards.
• Community Scientist Academy provides an opportunity for community stakeholders to learn more about translational research and the various ways they can get involved via a six-week program (meets once per week)
• Consultation and Feedback from CE Program staff and our Community Advisory Boards (Faculty, Central Ohio, and Southeast Ohio/Appalachia)
• CE Pilot grants through the CE Program’s partnership with the CCTS Pilot and
Collaborative Studies Program
• Appalachian Translational Research Network (ATRN) provides a network of academic research institutions designed to establish partnerships and connect with communities and organizations in the Appalachian Region
The Comparative Animal Core (CAC) provides an integrated platform for preclinical and translational research and training for studies involving animals with natural disease. The CAC is made up of two major components: the Animal Tissue Biorepository and the Clinical Trials Office.
This core also functions as the OSUCCC's Veterinary Clinical Research Support Shared Resource (VCRS SR), which designs and conducts clinical trials in companion animals with spontaneous diseases to evaluate novel diagnostics and therapeutics and collects biospecimens, such as tissue biopsies, serum, plasma and urine, in support of comparative cancer research. The overriding goal of this resource is to advance the diagnosis and treatment of disease in veterinary patients while enhancing the health of humans through comparative and translational studies.
Comparative and Translational Medicine
The goal of the Comparative and Translational Medicine (CTM) program is to leverage natural diseases in animals to create an integrated platform for collaborative research, therapeutic interrogation, cross discipline training and outreach across OSU, NCH and its partners. The program supports interactive, multi-disciplinary research via several initiatives. With the overriding goal of advancing the diagnosis and treatment of diseases in veterinary patients while enhancing the health of humans through comparative and translational studies.
CTM initiatives include:
Nodes of Comparative Medicine
The nodes of comparative medicine consist of organized teams of researchers and clinicians focusing on specific health areas of high translational potential. Node leaders work to connect researchers and veterinary clinician-scientists to facilitate veterinary clinical trials on the translational spectrum.
• Infectious Disease (Michael Oglesbee/Oglesbee.firstname.lastname@example.org)
• Comparative Oncology (Joelle Fenger/Fenger.email@example.com)
• Renal Disease and Pathology (Rachel Cianciolo/Cianciolo.firstname.lastname@example.org)
• Neuromusculoskeletal Disease (Sarah Moore/Moore.email@example.com)
Translational Therapeutics Think Tank (T4)
The mission of the Translational Therapeutics Think Tank (T4) is to provide consultation and guidance for investigators working in novel drug/device discovery and development within the OSU and NCH communities. Investigators can request a meeting with a panel of content experts customized to their specific research-related questions by visiting go.osu.edu/ccts-t4.
The Blue Buffalo Veterinary Clinical Trials Office and the Biospecimen Repository
The BBVCTO has a mission to advance the diagnosis and treatment of disease in veterinary patients through interdisciplinary collaborative research efforts within the CVM, OSU and NCH communities while improving the health of humans through comparative research efforts.
The BBVCTO is available to:
• Assist with protocol development
• Interface with industry sponsors
• Confirm compliance with appropriate approvals
• Formulate and review study budgets
• Conduct studies according to GCP guidelines
• Generate CRF’s and data capture/REDCap
• QA/QC Data
• Recruit patients through various marketing tools
• Oversee and assist with clinical trial performance
• Provide study financial management
• Collect, process, and store study samples
• Biospecimen sample requests are available at: eramp.osumc.edu
Research Informatics is a group of highly trained software engineers, IT professionals, and biomedical informatics technicians that is a part of the Department of Biomedical Informatics (BMI). This team leverages the skills and tools that exist within OSU’s Department of BMI and OSUWMC’s Information Technology Department (OSUWMC-IT) in order to provide an informatics-based catalyst in support of novel, multi-disciplinary clinical and translational science endeavors.
The ISP program offers free consultations on inclusivity in research program design to NCH/OSU faculty investigators and study teams interested in integrating special populations in research, as well as pilot funding to support research initiatives involving groups that are frequently underrepresented in clinical and translational research. The ISP pilot program supports new applications annually and focuses on research programs aimed at the study of a special population or who are seeking to enhance an existing program to be more accessible to diverse participants.
Assistance for medical faculty and investigators from pre-clinical to clinical trials, as well as guidance for external partners and collaborators through the regulatory landscape.
Services include consultation in design of research with behavioral components; selection of behavioral measurement techniques and instruments; assistance in behavioral outcomes sections of grant applications and manuscripts; and assistance with collection, scoring, and analysis of behavioral data; and assistance with qualitative methods.
Services include biospecimen processing, banking, distribution, and virtual microscopy.
Streamlined coordination of services necessary to initiate clinical research projects, regardless of funding source, as well as provision of staff and/or services to manage studies according to Good Clinical Practice and federal, state, and institutional regulations and guidelines.
IMF grants are available to physicians, psychologists and other clinical staff at with an OSU faculty appointment, as well as residents and fellows. Research Institute faculty are eligible if collaborating with an NCH clinician. Fellows can apply for up to $10,000 and faculty can request up to $50,000. There are 3 application cycles annually, with special RFAs announced to target areas of interest.
IT assistance to researchers on data processing from acquisition, curating and management to analysis and visualization, including both clinical and non-clinical basic research data.
The Participant and Clinical Interactions (PCI) Program provides administrative support for investigator-initiated multicenter clinical research trials. The PCI Program is tasked with providing facilities and resources to investigators conducting human subjects research at OSU and NCH.
PCI connects investigators to local established clinical and translational research entities, leveraging collective resources and expertise of:
• OSU College of Medicine Clinical Trials Management Organization (CTMO)
• OSU Comprehensive Cancer Center Clinical Trials Office (CTO)
• OSU Clinical Research Center (CRC)
• NCH Clinical Research
PCORI and NIH proposal development services are provided through the CCTS PCI program formulticenter clinical research trials for:
• Study budgets
• Project management plans
• Leadership / Organizational plans
• Securing letters of support
The purpose of the Pilot Translational & Clinical Studies (PTC) Program of the OSU CCTS is to fund meritorious pilot projects by cross-disciplinary teams from The Ohio State University and Nationwide Children’s Hospital to generate preliminary data and refine research strategies for subsequent extramural grant applications or towards commercialization. The mission of CCTS Pilot Programs (PTC) is to catalyze innovation, translational science, team science and workforce development by funding or co-sponsoring projects. This is done through interdisciplinary teams with patient and community engagement to develop novel methods, tools, therapies, technologies and policies. The PTC program employs innovative funding mechanisms and programming dedicated to enhancing the quality and efficiency of translational endeavors.
Recruitment and Retention can help design those first touch points with the community and share best practices to help researchers achieve their recruitment/retention goals. The goal of every research study is one that is fully recruited with high retention. In order to make that goal a possibility, research teams are encouraged to request recruitment/retention consultation early in the planning and design stages of their studies to reduce the burden of study participant recruitment, which can often be more challenging than expected.
Navigating the federal and local regulatory landscape can be time consuming and confusing. The goal of the regulatory knowledge and support services is to advise research studies in navigating the requirements for federal and local regulations. In order to make that goal a possibility, research teams are encouraged to request regulatory consultation early in the planning and design stages of their studies.
The CCTS Regulatory Knowledge and Support Service provides expertise in revealing and resolving such issues that are particular to any one study. The result is to create a robust environment for human subject research that not only meets the applicable rules and regulations, but promotes the conscientious conduct of these endeavors.
The Research Concierge provides complimentary consultative services to faculty and staff at The Ohio State University and Nationwide Children’s Hospital to navigate the complex research ecosystem and to connect with experts, resources and services at the CCTS and beyond. Since inception, the research concierge has assisted with hundreds of requests submitted by faculty, staff, students and the community.
Triage and funneling of requests towards CCTS programs; often the first point of contact for the CCTS, referral to centers, programs, cores, shared services and other resources across the OSU and NCH campuses; creative problem solver and integration support to resolve research concerns.
Identify and promote funding opportunities; match investigators with specialized faculty expertise for concept development and team science; communication liaison to address research needs rather than bounce from person to person looking for answers; assists with design, analysis, data collection and management plans, ethics considerations and regulatory plans; and to identify gaps and create new services to enhance research operations and efficiency.
Identify research resources, services, programs or specialized equipment for investigators; navigation of complex research infrastructure; interpret and facilitate compliance with research and clinical policies and procedures; introduction to key leaders and staff.
Formal presentations to groups and welcome consultations for new faculty; promotion and marketing of the CCTS programs internally and externally; champion translational science to larger research community, internal and external partners and public.
A new national collaborative initiative aimed at improving investigator-initiated multicenter trial operations for Clinical and Translational Science Award (CTSA) consortium members across the US -including all investigators at OSU and NCH
The TIN provides services for all aspects of proposal development and execution including:
• Efficacy to Effectiveness (E2E) consultations on clinical trial design
• Development of robust recruitment plans and materials Serving as a Central IRB
• Serving as a clinical and/or data coordinating center
The OSU CCTS facilitates and supports the translation of scientific discoveries into innovations that improve health. To achieve this mission and advance translational research, the CCTS is awarding vouchers to provide funding support to investigators who require assistance from an eligible Ohio State University or Nationwide Children's Hospital core service to enable preliminary work and generate data for new or ongoing projects and/or to secure fee-based core services for expert consultation services with the ultimate goal of furthering clinical and translational research.
These awards are intended to be used on projects that are ready for services immediately (“just in time” data). The CCTS will award OSU and NCH investigators vouchers worth up to $3,000 in core services per investigator and per project. New to the program is the CCTS Collaboration voucher. The goal of this voucher is to increase collaboration across colleges and institutions. Projects with investigators from 2 or more colleges or institutions are eligible for up to $5,000 dollars in funding.
• Employing gamification for workforce development, including GCP training.
• Creating mini-modules for key clinical translational topics.
• Supporting and presenting at FDA Workshops.
• Developing a catalogue of publically available clinical research training at OSU and NCH.
• Connecting and collaborating with regional CRP workforce development initiatives.
• Connecting and collaborating with CTSA hubs through workforce development virtual
• Exploring innovative methods for training delivery such as virtual reality.
• Exploring ePortfolios for CRP workforce development.
• Leading activities of the DIAMOND Portal and sharing OSU/NCH trainings in DIAMOND.
• Researching personalized pathways for CRPs.
• Researching the CRP role of nurses.
• Establishing a CRP Network for Listservs, Mentoring, and Leadership development.
• Developing and launching a Competency-based Curriculum for CRP Onboarding.
• Being a resource for collaborative CRP training.
• Supporting research in CRP workforce development.
• Supporting NLighten expansions and dissemination.
• Serving leadership roles in the ACTS/NCATS Task Force CRP Workforce Development.
• Studying assessments of CRP competence.
The CNS/PNS Injury Core is located in N229 Wiseman Hall. The primary service of the Core provides standardized peripheral nerve injuries or spinal cord injuries. This Core provides behavioral tools commonly used in spinal cord injury studies. Although this support covers costs of the behavioral technician, it does not provide for equipment or animal per diem charges
The Campus Chemical Instrument Center (CCIC) was founded in 1981 as a unit of the Office of Research. The mission of the CCIC is to provide state-of-the-art research facilities for the entire campus in three areas: Nuclear Magnetic Resonance, Mass Spectrometry and Proteomics. Since the NMR, MS and Proteomics Facilities are central hubs for the Ohio NMR and Ohio MS Consortiums, respectively, all researchers in the colleges and universities of the State of Ohio have access to all facilities of the CCIC with the same user fees. The OSU Office of Research provides personnel support of the CCIC. Equipment funding has been provided by Ohio Board of Regents, National Institutes of Health, National Science Foundation, and Office of Research.
The mandate of the CCIC Mass Spectrometry and Proteomics (MSP) Facility is to provide state-of-the-art instrumentation and personnel expertise for a wide variety of research projects. Main areas of services we provide include i) proteomics, ii) metabolomics, and iii) general mass spec analyses for research groups. We also participate and provide support for grant applications and education. The Mass Spectrometry and Proteomics Facility at CCIC is an interdisciplinary unit, servicing faculty from the colleges of Biological Sciences, Education and Human Ecology, Engineering, Food, Agriculture & Environmental Sciences, Mathematical and Physical Sciences, Medicine, Optometry, Pharmacy, and Veterinary Medicine just to name a few. CCIC also serves scientists from other universities and industry within and outside of Ohio.
If you do not know what kind of service you need, please contact Dr Arpad Somogyi. Submit a Service Request Form through FOM – see instructions via link below. Please provide as much information as possible regarding the sample and desired analysis. Please note any special sample instructions or analysis instructions on the form. The more information we have, the better the results and the faster we can return data.
Bring sample(s) and the Service Request Form between 8AM & 5PM or mail to:
OSU Mass Spectrometry & Proteomics Facility
460 W 12th Ave, Rm 250 Biomedical Research Tower (BRT)
Columbus, OH 43210
Bring your Buck ID for access to our Facility in the Biomedical Research Tower.
Results are emailed and all data is electronic.
Samples are discarded after analysis, so please indicate if you would like to pick up any unused sample.
The CCIC NMR Facility is a state-of-the-art campus-wide core facility that currently houses nine high resolution Bruker NMR spectrometers (600 to 850 MHz) with a range capabilities: high-sensitivity cryoprobes for structural and dynamics studies of proteins, nuclei acids and their complexes, high-throughput sample changers (SampleCase and SampleJet) for metabolomics and drug screening for discovery, solid state probes for biomolecules and materials, micro-imaging and diffusion. The facility is located on both North Campus (CBEC building) and South Campus (Riffe building), which are within 15 minutes walking distance. This shared facility is one of the premier facilities of its kind in the US and is available to scientists within and outside of the OSU.
In addition, a cutting-edge ultrahigh field 1.2 GHz nuclear magnetic resonance (NMR) spectrometer has been funded by the National Science Foundation (NSF), which will be the centerpiece of the new National Gateway Ultrahigh Field NMR Center. Once commissioned, this next generation NMR instrument will be open to U.S. NMR researchers in the fields of biomolecular NMR of proteins and nucleic acids in solution and in the solid state, materials science, and metabolomics. The instrument will be run and maintained by CCIC NMR Facility staff.
About Facility Organization - the NMR facility operates under the administrative umbrella of the CCIC through the Office of Research (OR). It was founded in 1981 to provide state-of-the-art technology and services to all campus-wide researchers. The operation and service expenses are covered by user fees.
For citations please use this text: "Acknowledgement: This study made use of the Campus Chemical Instrument Center NMR facility at Ohio State University."
The OSU Campus Electron Optics Facility was established to provide state-of-the-art electron microscope services to OSU and the local community. It is a part of the Center for the Advanced Maturation of Materials (CAMM) in the Department of Materials Science and Engineering. Instrumentation: TEM - CM200, TEM - Tecnai F20, TEM - Titan3, TEM - CM12, FIB - Helios 600, FIB - Nova 600, SEM – ESEM, SEM – Quanta, SEM – Sirion, XRD - Bruker D8, XRD - Scintag Pad V, XRD - Scintag XDS2000, XRD - Philips XRG3000.
The Campus Microscopy and Imaging Facility (CMIF) serves University faculty staff and students as well as researchers outside Ohio State. The CMIF offers a full range of light, confocal, live-cell, super-resolution, and electron microscopes. Sample preparation equipment is available. Expert support and technical assistance enables users to collect and analyze high quality images.
This facility also functions as the Microscopy Shared Resource (MSR) which facilitates cancer research by providing an accessible centrally-organized resource with technical support for confocal, light, live cell microscopy, super-resolution microscopy and transmission electron microscopy. Highly qualified faculty and staff provide training and advice for sample preparation, processing fresh tissues, sectioning epoxy-embedded samples, basic microscopy, and advanced training in live animal multiphoton microscopy. The MSR, a part of the larger Campus Microscopy and Imaging Facility under the OSU Office of Research, is managed by the OSUCCC. The MSR is located within OSUCCC space in the Biomedical Research Tower. The ability to offer competitive pricing and exceptional service can be largely attributed to the generous support of outstanding institutional resources, including partnerships with the OSUCCC, the Office of Research, OSU Colleges and Institutes, and state and federal grants. The Microscopy Shared Resource (MSR) gives researchers access to state-of-the-art microscopes and to services ranging from standard light and electron microscopy to leading-edge, live-animal, multiphoton microscopy. MSR experts support high-level cancer research with the latest microscopy techniques.
The beginning of the 21st century brought growing concern about climate change, food security, poverty, and population growth. Atmospheric carbon dioxide levels have increased to 40% from preindustrial levels to more than 390 parts per million CO2. At the same time, there is growing concern over hunger with more than 1 billion hungry in 2009 according to the FAO.
The Carbon Management and Sequestration Center (CMASC) at The Ohio State University in Columbus, Ohio conducts research on the best methods for reducing atmospheric CO2 through sustainable land management practices. Simultaneously, CMASC investigates strategies to enhance food security, improve water use efficiency, and reduce poverty. The research team is led by Distinguished Professor Rattan Lal, research staff, PhD students, MSc students, affiliated universities and other collaborators and sponsors.
The mission of CAMM is to develop research tools for the accelerated insertion of new materials and optimization of existing ones. This is done by developing and integrating computational modeling and simulation with advances materials characterization. An integration of academia and industry, CAMM performs world class R&D and develops technologies, which are captured in products that create wealth and jobs and provides an enhanced educational process. Inputting significant effort in developing and integrating characterization and modeling, CAMM develops new research tools and methodologies to accelerate the insertion of new materials into commercial products.
The primary goal of the Center for Affordable Nanoengineering of Polymeric Biomedical Devices (CANPBD) is to develop polymer-based, low-cost nanomaterials and nanoengineering technology to produce advanced medical diagnostic devices, cellbased devices, and multifunctional polymer-nanoparticle-biomolecule nanostructures for next-generation medical and pharmaceutical applications. Although challenging, this goal provides opportunities for scientific breakthroughs, cutting edge technologies and novel interdisciplinary system integration. Fundamental science and engineering is one of the major foci of our center. In Phase I, many useful nanotechnologies, devices and nanoconstructs have been developed. Each has specific merits and value-added capabilities providing for near-term applications. Following this success, we plan to establish a nanotechnology pipeline in Phase II to address the need for (1) ‘up-stream’ fundamental science, (2) high risk technologies meeting long-term research objectives, and (3) ‘down-stream’ devices and nanoconstructs requiring integrated system-level effort.
The Center for Automotive Research (CAR) is an interdisciplinary research center in The Ohio State University’s College of Engineering. CAR research focuses on: energy, safety and the environment aimed at improving sustainable mobility. CAR offers state-of-the-art facilities for students, faculty, research staff and industry partners. With a concentration on preparing the next generation of automotive leaders, CAR is recognized for: interdisciplinary emphasis on systems engineering, advanced and unique experimental facilities, collaboration on advanced product development projects with industry and a balance of government and privately sponsored research.
In collaboration with the Departments of Mechanical and Aerospace Engineering and Electrical and Computer Engineering, CAR provides students the opportunity to complete a graduate specialization in automotive systems engineering. Further, CAR directly offers a certificate program via distance learning for industry practitioners. Finally, CAR provides facilities and support for six automotive undergraduate student project teams.
Our biostatistics faculty include nationally known experts on health metrics. Current research by the biostatistics faculty includes survival analysis, threshold regression methodology, cancer statistics, and environmental and occupational risk assessment. These partnerships result in well-designed studies and properly analyzed data.
Our experts collaborate with colleagues throughout the Ohio State Health Sciences campus as well as peers across the nation.
The CCBD has been set up to provide OSU faculty, staff and students as well as external users with access to state-of-the art laser spectroscopy instrumentation. The Center is a part of the Department of Chemistry and the Institute for Material Science and includes high quality laser laboratory space, filtered air, temperature control, conditioned power, and closed circuit laser water cooling system. The Center integrates all the equipment necessary to measure transient UV/Vis, fluorescence, infrared, and stimulated Raman spectra on femtosecond time scale
The Center for Design and Manufacturing Excellence (CDME) at The Ohio State University aims to enhance the manufacturing competitiveness of the United States on a global scale by focusing its efforts on both applied engineering and student experiential learning. The center’s novel approach to technology translation is executed in its 32,000 square-foot, advanced manufacturing facility on Ohio State’s West Campus. The facility is ITAR-compliant and houses more than $12 million worth of advanced manufacturing equipment.
CDME works with commercial and government partners on product development projects. Throughout these projects, undergraduate students gain hands-on, mentor-based experience integrating new technology into market-ready applications, providing Ohio State customers with the technology and workforce advantage necessary to compete in a global marketplace. The center employs two dozen industry hardened experts with more than 425 years of combined professional experience. These experts execute projects while supervising and mentoring CDME students.
CDME facilitates innovation to an incredible breadth of advanced manufacturing practices, including but not limited to:
· Additive manufacturing
· Artificial intelligence and automation
· Biomedical devices
· Machining and testing
· Materials and welding
· Molding and forming
CEMAS is a core facility at The Ohio State University established through funding from the Department of Materials Science and Engineering, the College of Engineering, the Office of Research, the Office of Academic Affairs, the Institute for Materials Research at Ohio State, and by the Ohio Development Services Agency and Ohio Board of Regents through the Ohio Third Frontier Program.
The vision of the Center for Electron Microscopy and AnalysiS (CEMAS) is to disrupt the stratification of disciplines in the characterization of materials. We will bring together multidisciplinary expertise to drive synergy and amplify our characterization capabilities, and thus challenge what is possible in electron microscopy. CEMAS has become the hub for business and academia for materials characterization. Our point of difference is our world-class multidisciplinary approach that enables academic and business partners to "see more" than ever before. We are the Center that breaks through the current characterization limitations in medicine, environmental science, energy materials, and beyond.
Our mission is:
To deliver a world-class capability that positions it as the leading Center in analytical electron microscopy in the world
To be the hub for multidisciplinary imaging research in physical and biological sciences at Ohio State
To revolutionize teaching and learning in advanced characterization techniques for students and researchers
To provide a flexible approach to allow external partners to access world-class characterization instrumentation and expertise
To be at the leading edge in the development of new techniques and method for electron microscopy.
The Center for Emergent Materials engages researchers from multiple disciplines to work in teams on scientific problems too complex for a single researcher to solve. The CEM, established in 2008, is located at The Ohio State University and funded by a National Science Foundation MRSEC award.
RNA research is an interdisciplinary endeavor that spans biology, medicine, agriculture, mathematics, physics, and chemistry. Ohio State’s Center for RNA Biology houses the single largest group of RNA experts in the country – more than 250 faculty, staff, students, and postdocs. The center’s mission is to advance life sciences research and education at the university by building on existing strengths in RNA biology, developing synergies through interdisciplinary initiatives and outreach, attracting and retaining outstanding faculty, and bringing the best graduate and postdoctoral researchers to the university.
The Center for RNA Biology is the home of 40 labs with a broad range of RNA-related Research. Our Center facilitates a monthly seminar series held on the second Tuesday of the month during the school year. Our Seminar series hosts world-renowned speakers from around the country to talk about their scope of work in the RNA field. The Center for RNA Biology also has a Student Organization as well as a competitive Fellowship Program. Please contact us for more information.
The Center for Resilience is an interdisciplinary research center dedicated to improving the resilience of industrial systems and the environments in which they operate. In a nutshell, the center believes that short-term risk management and long-term sustainability are two ends of the enterprise resilience continuum. To pursue this mission, the center has joined forces with a powerful network of engineers, scientists, and business scholars at The Ohio State University and collaborating institutions, leveraging over $20 million in ongoing research programs.
We are an interdisciplinary group of scholars in social, natural, and environmental sciences; applied economics; agriculture; engineering; health and medical professions; and the humanities. We offer a wide range of support services for research that applies to urban and metropolitan areas, rural areas, and broader regional issues. Some of our services include GIS data processing, spatial analysis, and cartographic services.
Our mission is to serve as a bridge across academia, industry, and the policy sector by providing spatial analysis of economic, social, environmental, and health issues in urban and regional settings in Ohio and beyond.
The Center for HOPES works with public institutions and private organizations in Ohio and neighboring states to achieve their goals through professional health services research.
The Center draws upon the academic knowledge and skills, networks, and resources at The Ohio State University to deliver high-quality, tailored research studies.
The experience of published, nationally recognized leaders in the field of health services research and an applied, collaborative approach to investigate issues in health care creates a positive, results-driven experience for clients.
ADVANCING THE PREVENTION, DETECTION, AND TREATMENT OF BRAIN INJURIES
The brain is the body's most complex organ. It makes us who we are. It is critical to our abilities to speak, think, remember, interact, and move.
The Ohio State University is advancing how we understand and approach brain injury as a chronic condition. Even mild brain injuries can have persistent, long-term effects that impact our future health and wellness. Understanding, detecting, treating, and preventing these effects is essential to solving the silent epidemic of traumatic – or rather, chronic – brain injury.
To accelerate discovery, our scientists and clincians are forming interdisciplinary teams that are translating knowledge, partnering with industry and community organizations, and expanding capacity to implement practical solutions.
Our researchers are:
Deepening an understanding of how brain injuries result in visible and chronic conditions and higher risk for dementia and movement disorders.
Studying the mechanisms of the immune system's response to neurotraumas that will inform pharamlogical, rehabilitative, and arts-based interventions.
Developing new approaches to imaging, sensing, and clinical data analytics that better detect, monitor, and predict the trajectories of brain injuries.
The Clinical Pathology Laboratories include the clinical chemistry, cytology and hematology laboratories. These laboratories provide diagnostic service and professional laboratory expertise to the Veterinary Medical Center, departments and research laboratories within the college and university and the university laboratory animal program. Samples from multiple species are analyzed daily using state-of-the-art automated equipment.
In addition to diagnostic services and specimen analysis, the clinical laboratories provide valuable case material for teaching veterinary medical students and preparing residents for specialty board certification in veterinary pathology, clinical pathology, internal medicine, and surgery.
The Center’s mission is to promote and provide high quality clinical education and reliable assessment of skills and procedures, with the ultimate intent being to advance patient care. The Center allows Ohio State to expand existing programs, launch new instructional techniques, and employ new outcomes assessments with the goal of training competent, compassionate professionals while fostering educational research.
The Clinical Translational Science Shared Resource (CTSSR) team works closely with clinical and translational scientists to develop a customizable portfolio of biomarker assays in order to provide innovative, correlative science studies associated with early-phase solid tumor oncology clinical trials.
The Clinical Treatment Unit and the Clinical Trials Processing Laboratory Shared Resource (CTU/CTPLSR) enable OSUCCC – James investigators to conduct successful phase I and phase II clinical translational research in a methodologically sound, expedient and cost-effective manner.
The CTU is an ambulatory phase I unit in the OSUCCC – James that specializes in treating early clinical trial patients who require intense monitoring or complex correlative sample collection and processing.
The CTPL enhances research quality by providing dedicated staff for high-volume procurement, processing, storage, delivery and shipment of research specimens critical to the correlative studies component of OSUCCC – James clinical trials.
The CTU/CTPLSR experts work closely with other OSUCCC – James Shared Resources, including the Clinical Trials Office, Pharmacoanalytical, Leukemia Tissue Bank and Biorepository, and Biospecimen Shared Resources. These collaborations provide protocol review and feasibility assessment, specimen kit assembly and specimen distribution to internal and external research laboratories.
The Clinical Trials Office (CTO) provides a centralized resource to facilitate the development, implementation and management of clinical trials at The Ohio State University Comprehensive Cancer Center.
The Cancer Diagnosis Program of the National Cancer Institute (NCI) initiated and supported the existence of the Collaborative (AKA Cooperative) Human Tissue Network (CHTN) in 1987 and therefore with the beginning of 2015 is entering its 29th year. The major goal of the CHTN is to facilitate the use of human tissues in biomedical research for basic and applied scientists from academia and industry to accelerate the advancement of discoveries in cancer diagnosis and treatment. The CHTN operates on a unique prospective procurement model rather than a banking model working directly with investigators to determine the appropriate tissue sources (e.g. surgery, autopsy, transplant) and tailor tissue-processing methods to meet the research needs of an investigator.
The College of Arts and Sciences is often called the academic heart of Ohio State. Not just because of its size, but because this is where arts, humanities, and natural, mathematical, social and behavioral sciences can converge in unique and unexpected ways. When we combine different perspectives and expertise, we can better investigate critical problems through creative and scholarly inquiry, engage the public in reciprocal community collaborations, and deliver an exceptional education for Ohio State students.
Our college is the fourth largest public dental school in the United States and consists of ten academic divisions representing all major dental specialties. The divisions offer both patient care services and academic programs, allowing dentists to train as specialists. Also, our Outreach and Engagement activities include over 60 active programs and more than 42 extra mural sites, which continue to expand.
The College of Dentistry provides comprehensive patient care in an unparalleled learning environment with internationally recognized faculty and a supportive network of alumni and friends. In addition, our research programs provide students another dimension beyond classroom and clinical education. Students and faculty members are able to participate in both clinical and laboratory research in areas such as dental materials science, oral and maxillofacial pathology, hard tissue biology, microbiology, neuroscience, and immunology
Since our beginnings in 1895, the College of Education and Human Ecology (EHE) has valued learning as a lifelong process. The educators, researchers and professionals we help grow are critical to shaping academic success and health and wellness for generations to come.
To stay one of the best, academic institutions have to change with the times. We've evolved and you will receive a better education because of it.
Today, the education we provide is not limited to developing some of Ohio's best teachers. We train the next generation of our nation's financial advisors, dietitians, policymakers, exercise scientists, event coordinators, counselors, fashion merchandisers, childhood education researchers and many other experts. Together they improve society and make the human experience better for generations to come.
We create, transfer and preserve knowledge in the disciplines of engineering and architecture for the purpose of enhancing economic competitiveness regionally, nationally and globally.
Today, our world-class teaching, research, and outreach -- the everyday work of our college -- impacts local, state, national, and global communities. Our goal is to be the standard of excellence for colleges of food, agricultural and environmental sciences.
All areas of the Ohio State College of Medicine are driven by our mission: to improve people’s lives through innovation in research, education and patient care.
We share a common vision: to work as a team shaping the future of medicine by creating, disseminating and applying new knowledge and by personalizing health care to meet the needs of each individual
The college offers outstanding preparation for leadership in the nursing profession at both undergraduate and graduate levels. The undergraduate program provides a strong academic and clinical background for entry into professional nursing, as well as leadership preparation at the baccalaureate level for those who are already registered nurses. The master's program is designed to prepare nurses for advanced practice roles as nurse practitioners, nurse midwives, clinical nurse specialists or administrators. A master's option is available to prepare clinical nurse leaders. Individuals with a baccalaureate or higher degree in another field can take advantage of the graduate entry option, which affords a streamlined approach to advanced nursing practice. The PhD program, which offers both post-master's and streamlined post-baccalaureate entry options, prepares nurse scientists and scholars who are skilled researchers and will advance the knowledge of the discipline. Finally, the college has recently introduced their newest program: the Doctor of Nursing Practice (DNP), an enhanced level of preparation for experienced nurses holding master's degrees.
The Ohio State University College of Optometry has a rich tradition of producing leaders in eyecare. Our faculty optometrists are recognized experts in providing specialty optometric care such as contact lenses, low vision rehabilitation, binocular vision, vision therapy, pediatric optometry, and medical eyecare. Our clinical services strive to provide personalized care to meet the visual and eye health needs of all patients. Our facilities are equipped with new technology and exam procedures to provide contemporary care to patients of all ages.
The Ohio State University College of Pharmacy advances the pharmacy profession and patient-centered care across Ohio and around the globe through innovative teaching and practice, ground-breaking research, and transformative outreach and engagement.
The College of Public Health at The Ohio State University is fully accredited by the Council on Education for Public Health (CEPH), the nationally recognized accrediting body for schools of public health. Additionally, the Master of Health Administration program is accredited by the Commission on Accreditation of Healthcare Management Education (CAHME), the primary accrediting agency for health management education. - See more at: http://cph.osu.edu/about#sthash.jg7D0x2R.dpuf
Whether you're a clinician, researcher or prospective student, or you're seeking clinical services for your pet or farm animal, you will find an innovative and supportive environment at Ohio State's College of Veterinary Medicine.
Established in 1885, the College has graduated more than 7,200 veterinarians and our alumni practice in all 50 states and 40 countries. Within Ohio, our graduates make up 85 percent of the practicing veterinarians in the state. Our comprehensive referral Veterinary Medical Center admits more than 35,000 animal patients each year, representing a wide range of species including companion, farm and service animals.
The Comparative Pathology & Digital Imaging Shared Resource (CPDISR) provides expert, readily available and affordable experimental pathology support to investigators conducting research for understanding the development and treatment of cancer using preclinical animal models and/or human tissues procured for translational research. Comparative pathologists affiliated with the CPDISR are familiar with normal anatomy
and physiology, and pathology of many animal species, including the potential impact of confounding factors such as age- and strain-related background lesions, pathogens, and husbandry practices on study outcomes. Recognition of lesions and their interpretation in the context of individual investigations provides a critical component to research incorporating animal models.
The CPDISR provides support for preclinical efficacy and toxicity animal studies as well as translational studies that utilize human tissues procured for research, and can tailor its support to the needs of a client. Comprehensive services provided by the CPDISR include: animal blood and other biofluid analyses; macroscopic and microscopic examinations of full tissue sets from various species of laboratory animals; comprehensive histology services on paraffin-embedded and frozen tissues, encompassing special histochemical stains and immunohistochemical stains optimized for animal and human tissues; preparation of tissue microarrays and grids for transmission electron microscopy; slide digitization and quantitative image analysis; and hands-on training and consultation.
The CPDISR also provides a referral service with expertise in animal model development, experimental design, optimal sample collection, data analysis and interpretation, and grant/publication preparation.
The Comparative Pathology and Mouse Phenotyping Shared Resource (CPMPSR) provides expert, affordable, experimental pathology support to OSUCCC – James researchers who use animal models to study human disease.
CPMPSR comparative pathologists are experts in the normal anatomy and physiology, and in background age- and strain-/breed-related lesions, infectious pathogens and husbandry practices of various animal model species. Lesion recognition and interpretation within individual investigations provides a critical component to research that incorporates animal models.
While intrinsically involved with the teaching and education missions of VBS, the combined service now offers anatomic pathology (necropsy, phenotyping, biopsy, and slide evaluation), clinical pathology, and histology (including immunohistochemistry and tissue microarrays) support to researchers both within the CVM as well as throughout the Ohio State University, including Nationwide Children's Hospital. Services to non-University clients are by special prior arrangement.
This unique, specialized laboratory is dedicated to the characterization and analysis of electrically active deep level defects in semiconductors and insulators. The lab houses complete, state-of-the-art facilities to conduct a variety of capacitance and current-based trap spectroscopies applicable to semiconductors that include GaN, InGaN, AlN, GaAs, InP, AlInGaP, SiGe, SiC, InGaAsN, ZnO, ZnMgO, and others. Both conventional deep level transient spectroscopy (DLTS) and photocapacitance-based deep level optical spectroscopy (DLOS) facilities designed by EMDL researchers are used in various configurations, the latter of which allows for unprecedented trap characterization abilities for materials having bandgaps up to ~5.5 eV.
The mission of The Ohio State University (OSU) Department of Biomedical Informatics (BMI) is to improve people’s lives through innovation in research, education, and patient care. We seek to achieve this mission by pursuing the advancement of health and biomedicine through the development, application, and dissemination of novel biomedical informatics theories and methods capable of driving biological discovery, generating and translating knowledge, and advancing personalized healthcare.
The Department of Chemistry and Biochemistry teaching and research missions are supported by several core facilities – the Research Support Services (RSS). These facilities are available to all departmental researchers including graduate students, post-docs, research associates, and undergraduates. Services available include surface analysis by X-ray photoelectron spectroscopy, atomic force microscopy, nuclear magnetic resonance, mass spectrometry, Raman spectroscopy, X-ray diffraction, analytical ultra-centricucation, circular dichroism, femtosecond laser spectroscopy, high-precision machining, electronic diagnostics and design, scientific glassblowing, and various other techniques.
For more information or any questions about accessing the RSS resources - please contact:
Dr. Tanya Whitmer, Director of Research Support Services for questions about analysis and instrumentation or
Dr. Gerry Raimann, Director of Administration for questions about the production shops.
The Department is the recipient of a Neuroscience Center Core grant from the National Institute for Neurological Disorders and Stroke, which funds core facilities and services in Mouse and Zebrafish Genetics, CNS & PNS Nerve Injury, Rodent Behavior, Neurophysiology, Muscle Physiology, Xenografting and Imaging.
Our mission is achieving national and international distinction in education, scholarship, and public service; to educate skilled professionals in the basic and clinical medical imaging sciences, and allied medical professions; to create, evaluate and disseminate knowledge and technology; and to provide innovative solutions for improving the health of the general public.
Founded in 1974, The Department of Statistics at The Ohio State University has grown steadily over the last 40 years to become an internationally recognized hub of research in statistical science and of statistics education. The department currently has 23 tenure-track/tenured faculty members, 6 professors emeriti in residence, and 4 associated faculty members with expertise in statistical education and consulting. The department also regularly hosts visiting scholars from around the world.
In terms of its research profile, the department aims to contribute to virtually all areas of statistical science, including the development of novel statistical theory and methodology. Specific areas of excellence include Bayesian statistics, spatio-temporal statistics, statistical learning, and biostatistics. Research is directed toward modern and emerging areas of interest. For example, in concert with the big data or data science revolution, many faculty members include high-dimensional analysis and computing as primary foci of their research programs. A large portion of the department’s faculty and students are involved in interdisciplinary research and make significant scientific contributions beyond the field of statistics. Faculty members are highly successful at securing competitive grants from various research funding agencies, including the National Science Foundation (NSF) and National Institutes of Health (NIH); research expenditures from these grants typically ranges from $1-2 million per year. In addition, the department is a partner in administering the NSF-funded Mathematical Biosciences Institute on the Ohio State campus.
We have world-class facilities and resources:
Within The Ohio State University Heart and Vascular Center, College of Medicine and Wexner Medical Center, we share a commitment to providing our patients with the most comprehensive healthcare options available.
Similarly, within The Dorothy M. Davis Heart and Lung Research Institute, we have a commitment to our investigators to provide them world-class facilities and technologies to push the boundaries of science.
With a dedicated seven-floor building and space across the campus, The Ohio State University Wexner Medical Center Dorothy M. Davis Heart and Lung Research Institute is now one of the largest heart and lung research institutes in the world. Our physicians and scientists have access to cutting-edge technologies in imaging, cell biology, genetics, bioinformatics and statistics, flow cytometry, mass spectrometry, electron paramagnetic resonance spectroscopy, metabolic profiling and animal physiology. Through collaborative efforts with the College of Medicine Office of Research, our investigators have a wealth of resources available for research, education and training.
The Electronic Materials and Nanostructures Laboratory (EMNLAB) is a group within the physical electronics branch of Electrical Engineering at The Ohio State University. The group focuses on using a wide array of analysis, processing, and growth techniques to investigate the surface, interface, and ultrathin film properties of semiconductors. The group is led by Dr. Brillson and consists of two full-size laboratories that house some of the latest surface analysis equipment.
Provides technical expertise, equipment and consultation for conducting electrophysiological studies.
Uses extracellular or patch clamp recordings to screen for alterations in synaptic transmission, such as measurement of EPSP or EPSC or alteration in LTP or LTD, in cerebellar, hippocampal, hypothalamic, and spinal cord slices.
erforms electrophysiological studies of voltage- and ligand-channels using isolated or cultured neurons.
The ElectroScience Laboratory is a major "Center-of-Excellence" within the Ohio State University Department of Electrical and Computer Engineering and is one of the largest Radio Frequency (RF) research laboratories in the world. Equipment and Facilities include Compact Radar Range, RF/Microwave Facility, Ceramics Fabrication Facility, LTCC Fabrication and Packaging Clean Room, Integrated Wireless Communication Systems Lab (IWCSL), Distributed-Memory Parallel Supercomputer, Northrop Grumman APN-241 Aircraft Weather Radar, Optics Facility, Automotive Measurements Facility, PCB Prototyping Facility, Printing on Polymers, Remote Sensing Lab, RFID Lab.
The ERC/NSM is the leading university associated group in North America conducting R&D and providing education in metal forming (stamping, sheet & tube hydroforming, forging) since 1986. In addition to training students, the ERC/NSM conducts R&D projects for government agencies, e.g. National Science Foundation, and for a Consortium of companies worldwide as well as individual companies, on a confidential basis.
ENCOMM is an interdepartmental, intercollegiate and interdisciplinary center with the goal of nucleating and fostering collaborative teams in the area of materials research. This mission is carried out through three principle activities:
The hosting of a weekly internal seminar wherein faculty can speak to faculty about their current research with the goal of soliciting input and recruiting partners with complementary expertise
A seed funding program (closely allied with the CEM and IMR) to support these team-based research projects until they are competitive for external block funding
Support for open-access research infrastructure and technical support staff to bridge between the technical capabilities of individual research groups and facilitate the expansion of individuals and teams into new areas of research
These activities serve both to promote the most effective aspects of interdisciplinary science and to knit together the materials community across the Ohio State campus.
The Flavor Research and Education Center (FREC) works to understand drivers of flavor perception and, ultimately, food choice. We have built a holistic analytical platform that combines our extensive expertise with modern and advanced instrumentation to investigate and address unique and challenging aspects of flavor discovery.
Our services include chemical profiling of non-volatile and volatile compounds in different food matrixes, quantification of aroma and flavor compounds, identification of off-flavors, activity-guided isolation of key bioactive compounds, characterization of flavor interactions—including the discovery of flavor modulating compounds, and sensory analysis as part of analytical projects.
The Flow Cytometry Shared Resource (FCSR) provides state-of-the-art flow cytometry analysis and sorting of cell populations using selected cellular markers. Flow cytometry is a critical technology for cancer research, and the ACSR is used extensively by all scientific programs in the OSUCCC – James and by the broader Ohio State research community.
Researchers can learn more about the use and application of flow cytometry in several ways, including scientific seminars, marketing at cancer-specific meetings, instrumentation overviews and application workshops. Additionally, the Mid-Ohio Cytometry Associates “users’ group” meets regularly to discuss relevant cytometry issues and to generate educational opportunities.
The mission of the Food Innovation Center is: to improve global life quality by inspiring sustainable multi-disciplinary food solutions. The Food Innovation Center brings together more than 115 faculty members and 18 associate members from 13 colleges to collaborate in teams that tackle food needs within and across four broad themes: Foods for health: Improving human health through food, Biomedical nutrition: Discovering the medicine in food, Food safety: Promoting safe food, and Global food strategy and policy: Working toward a healthier, hunger-free world.
A FUTURE OF PERSONALIZED NUTRITION FOR GLOBAL OPTIMAL HEALTH
Many costly and preventable chronic conditions — diabetes, heart disease, hypertension, dementia and certain cancers— are heavily influenced by our diets. The mission of the Foods for Health Discovery Theme is to promote optimal health for individuals and communities through the application of scientific approaches across the food-nutrition-health continuum.
Metabolomics is one such innovative scientific approach that allows us to think about important research questions in a novel and powerful way. Our goal is to rise to eminence in this field by establishing research, teaching and outreach excellence. Integrating multiple -omics technologies and capitalizing on the 'Omics Revolution' will allow us to better understand an individual's unique disease and determine what foods and nutrients can best be tailored to maintain their overall health and well-being. Metabolomics also can provide us with valuable information on the effects that food preparation and processing can have on the nutritional quality of the foods we consume. The grand objective in the utilization of these technologies is a future of personalized nutrition for global optimal health.
With all seven Health Sciences Colleges and a top-ranked academic Medical Center and Comprehensive Cancer Center as well as Colleges of Food, Agricultural & Environmental Sciences, Education & Human Ecology and Arts & Sciences all co-located on one campus, Ohio State is well-poised to collaboratively address the complexities of food and nutritional problems in ways that enable personalized prevention and medical care, dietary recommendations, and food-based interventions to improve health and prevent disease.
By connecting our faculty expertise and students to state-of-the-art technology and public-private partnerships, our interdisciplinary teams are making discoveries in food and nutritional metabolomics for health. Unprecedented insights in individual biochemical variability provide the foundation across diverse disciplines for:
Developing and using state-of-the-art analytical and informatics technologies to comprehensively identify and profile metabolites of nutrients and other bioactive food compounds in foods and biological samples.
Integrating -omics data sets to correlate unique features of an individual's metabolic profile to thier unique characteristics.
Discovering new biomarkers that define subtypes associated with wellness and disease.
Understand the effects that food preparation and processing can have on the nutritional quality of the foods we consume.
Developing personalized food and nutritional interventions to improve health.
Building a broad-reaching 'crops-to-clinic-to-consumer' network.
Committed to creating a healthier future for individuals and populations, our teams are leading new scientific approaches that integrate foods and nutrition, -omics, and health.
The Gas Dynamics and Turbulence Laboratory (GDTL) at OSU has been engaged in application guided fundamental research in gas dynamics, aeropropulsion, aeroacoustics, aero-optics, flow control, and advanced laser based flow diagnostics since late 1980s.
Gas turbine engines are of central importance to the global transportation and energy generation network. With applications for aircraft propulsion (jet engines), power generation, and many other purposes, improvements in the efficiency, reliability, or emissions of these engines can have far-reaching impacts. The Ohio State University Gas Turbine Laboratory seeks to combine the best aspects of academic and industrial research to advance the state-of-the-art in gas turbine design. Current research focuses include measurements and predictions for cooled full-scale turbines operating at scaled conditions and for flow inside the blade internal cooling passages. In addition, there are multiple aeromechanics research programs investigating the effect of engine-speed blade tip rub events as well as a variety of damping and monitoring techniques. All research projects are performed in close collaboration with industrial partners to ensure that the results are representative of engine conditions and relevant to current design questions.
The Gear and Power Transmission Research Laboratory, formerly the Gear Dynamics and Gear and Power Transmission Laboratory, is a research group at The Ohio State University in Columbus, Ohio, dedicated to aiding sponsoring industries and government agencies by
1) enhancing gear and power transmission technology through fundamental and applied research and transfer research results,
2) providing graduate and under graduate students with applied educational and research opportunities in gear and power transmission related disciplines, and
3) keeping sponsors updated on latest gear and transmission technologies.
Modeling human disease in mouse provides a powerful tool for elucidating mechanisms and interrogating experimental therapeutics. The Genetically Engineered Mouse Modeling Core (GEMMC) is available to investigators who work or intend to work with mouse models of human disease.
The Genomics Shared Resource (GSR) offers instrumentation and expertise for DNA and RNA analyses using Sanger sequencing, genotyping, real-time PCR, Affymetrix GeneChips, NanoString nCounter digital analyses, next-generation sequencing and library generation, nucleic acid extraction, spatial transcriptomics, and quality control for RNA, DNA and proteins. OSUCCC members and non-member investigators have unlimited access to training, consultation, troubleshooting and assistance in experimental design.
Ohio State's Glassblowing Facility can meet all of your needs for repair, modification and custom design of scientific borosilicate (Pyrex) or quartz glass apparatus. In addition, the shop can reduce your costs by reproducing standard catalog glassware (many designs on file in our shop library). Our glassblower is the third generation in a family of glassblowers and has been recognized by his peers by being awarded The Andrews Glass Award for best technical paper at The American Scientific Glassblowers Symposium, 1999 (see photo of liquid nitrogen cooled carbon monoxide laser). He is readily available for consultation on intricate design work and can perform on-site repair work in your lab as well as all in-shop services.
The Global Arts + Humanities Discovery Theme is the gateway to integrated arts and humanities at The Ohio State University. Global Arts + Humanities facilitates, supports, and leads innovative trans-institutional collaborations and cross-disciplinary research, experiential learning, and community partnerships that enhance the university’s capacity to foster cultural understanding and advance social change.
The Goldthwait Polar Library (PLR) contains materials relevant to the polar and alpine regions of the world.
The Goldthwait Polar Library was officially established in 1969, nine years after the establishment of the Institute of Polar Studies, now the Byrd Polar and Climate Research Center (BPCRC). The library is named after Dr. Richard Parker Goldthwait, the founder and first director of the Institute. Dr. Goldthwait donated his personal collection of reprints, journals and books to the Institute and that became the nucleus of the library.
The primary mission of the library is to support the informational needs of the research scientists and graduate students of the Center. Subject areas covered include: glaciology, Antarctic geology, global climate change, polar ecology, polar meteorology, and the history of polar exploration.
In 2013 the library completed the digitization of BPCRC publications. They are now available in OSU’s institutional repository, The Knowledge Bank (KB). Future publications will be added as they are published. Reports in the KB are open access.
The library is not officially a department library of the Ohio State University Libraries, but the monographic holdings are available in their online catalog. The library follows their circulation policies and procedures; most of the material circulates. PLR is the designation for the library in the online catalog.
Rare historical volumes in the library include Sir Ernest Shackleton’s The Heart of the Antarctic and The British Antarctic Expedition 1907-1909, signed by Shackleton and Sir Douglas Mawson, and signed copies of Admiral Byrd’s books, Little America, Discovery, Skyward, and Alone.
Medical Visuals, located on the 4th floor of Prior Hall at 376 West 10th Avenue, supports research and education through graphic arts. Services include medical illustration, graphic design, layout consultation, poster printing, and portrait photography. Trained in both art and science, our certified medical illustrator creates visuals that effectively communicate medical and scientific content to any audience. Award-winning graphics have been published in major medical and research journals including Cell and the Journal of Neurosurgery. Medical Visuals staff also designs informational graphics, conference brochures and promotional posters for scientific events. Medical Visuals is a primary campus resource for poster printing. Service-oriented staff consult with customers to create high quality professional posters on traditional paper or convenient foldable cloth material. Poster files can be uploaded conveniently online and proofs are generally available the same business day. Medical Visuals also provides studio portrait photography in Prior Hall. Digital portraits can be used for CVs, publications, presentations, and other promotions. For a complete list of Medical Visuals services, pricing, and hours please visit the Health Sciences Library web site.
The Health Sciences Library, located in Prior Hall, provides innovative services and resources to support research, education, and patient care for Ohio State’s faculty, staff, and students, targeting the Colleges of Medicine, Nursing, Dentistry, Optometry, Public Health, the School of Health and Rehabilitation Sciences, as well as the Wexner Medical Center and James Cancer Hospital and Solove Research Institute.
Basic reference service is available at the desk at the main entrance, and research consultations with librarians are available by appointment only. Other services available include poster design and printing, medical illustration, audiovisual assistance across the medical center campus, and access to a rich collection of electronic books and journals, databases, and print books and journals.
The Health Sciences Library also houses the Medical Heritage Center (MHC). The MHC preserves, promotes, teaches and celebrates the health care legacy of central Ohio as the essential foundation from which the future of the health sciences is born. Located on the fifth floor, the MHC’s holdings include rare books, archives, and medical artifacts.
The Human Tissue Resource Network (HTRN) provides a variety of services to researchers and clinicians at The Ohio State University Wexner Medical Center as well as basic and translational outreach programs throughout the United States and Canada. Services include biospecimen and biofluid procurement and processing, biobanking, histology, tissue microarray (TMA), immunohistochemistry (IHC), fluorescent in situ hybridization (FISH), chromogenic in situ hybridization (CISH) and molecular testing, and virtual microscopy and digital image analysis.
Three federally funded research programs are supported by the HTRN including the Collaborative (AKA Cooperative) Human Tissue Network (CHTN), the ALLIANCE for Clinical Trials and Oncology, and the OSU Comprehensive Cancer Center Total Cancer Care Program (TCCP) accompanied by corporate funding and department research programs.
HTRN sections that help to support these programs include the Pathology Core Facility (PCF), Tissue Archive Service (TAS), Research Tissue Procurement Service (RTPS), Specialty Labs including digital imaging and laser capture microscopy, and biorepository services.
This Core provides two services 1) Light Microscopy, and 2) Magnetic Resonance Imaging (MRI). Please see our Terms of Service for specifics regarding use of this Core.
The Imaging Core Laboratory (ICL) through the Wright Center of Innovation at The Ohio State University performs visual reads, quantification, lesion tracking, perfusion and metabolic mapping, pharmacokinetic analysis, quantification of lesion heterogeneity, 3D segmentation and rendering in addition to conventional methodologies such as RECIST / WHO, Volume tracking and morphologic characterization.
The Initiative for Food and AgriCultural Transformation
Strategic Research Targets, August 2020
InFACT is taking a transdisciplinary convergence research approach to systematically addressing knowledge gaps in the role of diversity in food system function. Transformational change is needed all along the set of activities and outcomes that comprise the human food chain today. A food systems framework for research broadly lists the activities making up a modern human food chain as producing, processing and packaging, distributing and retailing, and consuming food. These activities have outcomes that have been grouped into three categories: availability (from producing), access (from processing, packaging, and distributing including selling), and utilization (from consuming and including resulting health outcomes). InFACT research and scholarly activity focuses on contributing new knowledge, and facilitating innovation and discovery, where research could facilitate and leverage transformation. The research contributing to each of these three categories of outcomes is summarized below.
InFACT Scholarship Agenda to Transform Food Availability: Pathways to More Diversified Agricultural Landscapes
• Discover diversified farming systems that can contribute to greater economic, social and environmental benefits in agricultural production.
• Discover and explore how agricultural economies of scope can be achieved to support diversification of agricultural landscapes.
• Discover landscape designs and policies that enhance the viability of diversified agricultural systems.
InFACT Scholarship Agenda to Transform Food Access: Access and Value in Reimagined Food Supply Chains
• Explore, create, and test balanced and integrated supply chains from local to global scales in ways that increase access, food safety and transparency.
• Discover the means of reducing food waste across the supply chain from production to consumption, and turning remaining waste into raw materials for value added processing.
• Measure and expose inequities in food access among populations, and exploring new ways of increasing equity.
InFACT Scholarship Agenda for Transformation of Food Utilization: Food as a Foundation for Community Health
• Explore how food landscapes impact geographic patterns of food consumption
• Translate the multiple values and transitions in food culture and use into transformation.
• Discover creative new dietary patterns that improve health and well-being in communities.
Our mission is to explore how foodborne and nosocomial microbes can affect animal and human health. As a team of scientists, we seek to unravel the epidemiology and molecular mechanisms of foodborne and nosocomial pathogens, with emphasis on antimicrobial resistance, to improve health and well being of humans and animals.
A world free from the threat of infectious diseases
The Infectious Diseases Institute will generate solutions to the detrimental effects of microbes on the health of humans, animals, plants, and the environment for the benefit of society.
The IDI embraces the university’s shared values in how we conduct business and interact with individuals, both internally and externally. These shared values are:
Excellence: The IDI will strive for excellence in all endeavors, both large and small. The IDI will constantly evaluate current conditions and will be flexible and agile in order to make continuous quality improvements.
Diversity in people and of ideas: The IDI will be an incubator for new ideas in all areas, including research, education, community outreach, and resource stewardship. Diversity in people, and their thoughts and ideas, will be a key component in all IDI activities.
Access and affordability: The IDI will seek new revenue streams while adopting all available best practices to keep costs as low as possible, thereby positively contributing to the university’s overall financial portfolio to play a part in the president’s 2020 Vision.
Innovation: The IDI will be a pillar of innovation, transforming the way we think about infectious disease and microbiology research, education and outreach. The IDI will be a driving force in innovation locally and globally.
Collaboration and interdisciplinary endeavor: The IDI will push the boundaries in unprecedented ways to strengthen and increase existing interdisciplinary efforts and to foster new internal and external collaborations in the infectious disease and microbiology space, including non-traditional partners in various disciplines.
Integrity, transparency, and trust: Integrity, transparency, and trust will be bedrock qualities of the culture of the IDI and will be embedded in all IDI ventures.
Informatics Research & Development is a group of highly trained software engineers, IT professionals, and biomedical informatics technicians that is housed within the Department of Biomedical Informatics.In conjunction with the Ohio State University Wexner Medical Center IT (OSUWMC-IT) and the Center for Clinical and Translational Science (CCTS), IR&D offers the following services:
- IHIS for Research
- Research Informatics Services Core
- Software Engineering
• Foster collaboration among researchers from multiple academic disciplines to collaboratively develop solutions to complex cybersecurity and digital trust issues.
• Prepare the next generation of workers, scholars and leaders to develop robust and effective cyber trust solutions.
• Partner with other educational institutions, government, military and industry to identify emerging cybersecurity issues and find ways to address those needs through research, education and collaboration.
Hesham El-Gamal, chair of the Department of Electrical and Computer Engineering and Helen Patton, Ohio State’s Chief Information Security Officer, will serve as interim co-directors of the institute. The Office of Research will provide initial oversight and resourcing.
The Institute for Ergonomics at The Ohio State University is dedicated to ensuring safe and effective designs of work environments and consumer products. This is accomplished by determining both the physical and cognitive capabilities and limitations of people, and understanding how one's performance is affected by using different tools, work practices, and support technologies.
The Institute for Materials Research represents more than 200 faculty members and research groups engaged in materials research from 6 colleges and 20 departments at The Ohio State University. With a network of state-of-the-art facilities throughout these departments and colleges, IMR provides coordination for a dynamic, world-class and multi-disciplinary materials research community that incorporates science and engineering from the sub-nano to macro scales, from soft to hard materials, from basic phenomena to devices, and from biology and medicine to agriculture, energy, communications, transportation and computation. IMR has a special mission: to create and sustain a coordinated, state-of-the-art environment that fosters collaborative, interdisciplinary research in the science and engineering of materials that addresses the future needs of society.
To see research resources under IMR please click the Institute for Materials Research Collection link at the bottom of the page.
In 1998, President Kirwan and the Board of Trustees established the Spectroscopy Institute, as an interdisciplinary venture focused on capitalizing and coordinating OSU excellence in spectroscopy. The founding Director was Prof. Terry Miller, Ohio Eminent Scholar and Professor of Chemistry.
The mission of the Spectroscopy Institute was to solidify OSU as the world-wide center of molecular spectroscopy, build upon OSU emerging strength in ultrafast technology and bring together the appliers of these technologies with the creators of the underlying sciences. Which under the direction of Prof. Terry Miller the institute effectively served the mission bring ties between Chemistry and Mechanical Engineering.
Today under the direction of Prof. DiMauro the new institute, “Institute for Optical Science” aims to identify and facilitate OSU faculty to capitalize on national interdisciplinary initiatives in the optical sciences. The Institute for Optical Science goals are the creation of an OSU community of multidisciplinary researchers in the optical sciences, coordinate on-campus and regional focus groups and centers that eliminate traditional academic boundaries at the research level and identifies strengths in interdisciplinary photon science research. Institute for Optical Science will accomplish these goals through interdisciplinary workshops, seminars and schools within the OSU community.
The Integrative Cardiovascular Physiology Core Laboratory (ICP) will support cardiovascular research using large research animal (e.g. rabbit, canine, porcine) models of human diseases. The core will provide both equipment and staffing support to assist investigators in the DHLRI. Equipment is available for cardiac echocardiography, hemodynamic and electrophysiology studies.
The core has the following equipment available:
1) GE Vivid 7 Echocardiograph
2) GE Mac-Lab IT hemodynamic and Cardiolab Electrophysiology amplifier with RF ablation interface and Image capture capability Bloom Four Channel Programmable Stimulator GE C-arm fluoroscope.
The DHLRI Interventional Cath Core fosters the development of interventional devices, therapies, and techniques by providing a translational laboratory setting where basic research findings can be developed into clinically relevant treatments for cardiovascular diseases.
The Non-GLP core is set up to accomadate a wide variety of interventional cardiac procedures using large animal models. Minimally invasive chronic procedures are permitted in this space. Non-cardiac studies can also benefit from the use of fluoroscopic guidance allowing real time x-ray confirmation during procedures. Orthopaedic groups have found it useful for guiding injections into joints. The aide of a contrast agent make it possible for surgeons to look for leaks following procedures in the GI tract.
The core is equipped with an OEC 9800 mobile C-arm with cardiac package and digitally archived images.
Support equipment include an anesthesia machine, ventilator, basic monitoring equipment (ECG, pressue, pulse Ox), cautery, IV pump, and power injector.
The John Glenn College of Public Affairs is the place to launch a lifetime of making positive change in the world. Whether you see yourself tackling homelessness in your community, taming the growing national debt, or creating educational opportunities for impoverished women around the globe, the Glenn College’s undergraduate and graduate degree programs will prepare you with the skills, knowledge and experiences to get things done.
What separates students at the Glenn College from everyone else? Our graduates have the tools to make their passion their life’s work. We’ll teach you how to turn your passion into policy. The Glenn College experience helps you make a change in the issues that matter to you.
The Kirwan Institute for the Study of Race and Ethnicity is an interdisciplinary engaged research institute at The Ohio State University established in May 2003. It was named for former university president William E. “Brit” Kirwan in recognition of his efforts to champion diversity at OSU.
Our goal is to connect individuals and communities with opportunities needed for thriving by educating the public, building the capacity of allied social justice organizations, and investing in efforts that support equity and inclusion. Here at the Kirwan Institute we do this through research, engagement, and communication.
Our mission is simple: we work to create a just and inclusive society where all people and communities have opportunity to succeed.
LCM is able to capture a relatively pure population of cells for downstream molecular analyses from paraffin embedded or frozen tissues. Cells are collected on a 6 mm capsure cap for DNA/RNA/Proteomic analysis. The dissection process itself is simple although special care must be taken in tissue handling, staining, and preparation to ensure that cell capture will be successful.
The Laser Capture Molecular (LCM) Core of The Ohio State University Medical Center (OSUMC) has been set up to enable investigators to incorporate the benefits of laser capture microdissection in their individual research projects. This exciting technology which was developed at the National Institute of Health helps to overcome the heterogeneity of tissue to isolate specific and pure populations of cells.
The Leukemia Tissue Bank Shared Resource (LTBSR) helps scientists translate basic research to the clinical setting by providing central collection, processing and storage of tissue samples from patients with leukemia, myeloma or lymphoma enrolled on Ohio State University Comprehensive Cancer Center – James Cancer Hospital and Solove Research Institute (OSUCCC – James) protocols. These samples are available to investigators at Ohio State and to outside collaborators who study the cellular and molecular properties of these diseases. The ability to examine tumor cells from patients is an essential part of determining the causes of cancer and developing new and effective treatments.
A National Cancer Institute (NCI)-sponsored biorepository, the LTBSR has more than 40,000 vials of cryopreserved viable cells and 13,000 vials of matched frozen plasma and/or serum samples from more than 4,000 patients treated for leukemia and other malignancies.
The machine shop is equipped with Manual and Computer Controlled ( CNC ) machinery for high-precision fabrication of mechanical and optical instrumentation using a very wide spectrum of material.
Consultation of Design
Turning and Milling
Welding (MIG and TIG)
Helium Leak Test for Vacuum Welds
Soldering and Silver Brazing
We train faculty, staff and students to utilize walk-up mass spectrometers for chemical compound identification and/or confirmation.
The Medicinal Chemistry Shared Resource (MCSR) provides medicinal chemistry support to investigators at the OSUCCC – James and to other academic and commercial institutions. It integrates the expertise of multiple disciplines, including synthetic and process chemistry, instrumental analysis and molecular pharmacology.
Semiconductor Processing Cleanrooms for Microfabrication includes 4000 square feet of class 100 and 1000 areas with additional associated laboratory space. There are facilities to process and fabricate silicon integrated circuits and III-V devices, and this capability has been demonstrated by the implementation of circuits in a variety of technologies (MOS, bipolar, FETs, optoelectronics, and photovoltaics). The processing equipment include a Technics Planar Etch II Plasma Reactor for dielectric deposition, hydrogen processing, and etching; ICP/RIE and E-Beam Photolithography; CHA 4-Pocket electron beam evaporator; NRC filament evaporator; ellipsometer; DekTak profilomiter; Karl Suss MJB-3 mask aligner; Kasper and Cobilt aligners and associated photolithography equipment; annealing, oxidation and diffusion furnaces; a pulsed laser deposition facility; West Bond wire bonder; Kenworth probe station with Hewlett-Packard 4145; 4-point probe; wet chemical clean benches, etc. In addition to ECE faculty, staff and students, the facilities are available to researchers from Physics, Material Science, Chemical Engineering, Chemistry, Mechanical Engineering, Welding Engineering and from outside Ohio State University. Arrangements for access by non-ECE Department personnel can be made by contacting Cleanroom Manager James Jones.
The Biomedical Research Tower (BRT) is a 10-story, 403,000-square-foot facility housing more than 180,000 square feet of lab space. The BRT is the largest research facility on the OSU campus, nearly doubling the amount of biomedical research space on campus.
Within the BRT (lower level), the Microimaging Laboratory is housed. It serves as part of the advanced structural, functional and molecular animal imaging infrastructure. The facility is part of the Wright Center of Innovation in Biomedical Imaging resources/services.
The DHLRI Microscopy Core Lab provides instruments for both wide-field and confocal microscopy. Specimens can be imaged by either transmitted light or epi-fluorescence. Images can be captured as single planes, z-stacks through the depth of the specimen, or as time-series. The core also has software for post-acquisition processing and analysis, as well as 3-D reconstruction of z-stack images. A tunable infrared laser is available for multiphoton fluorescence imaging in live specimens. Core personnel are available to assist you in instrument setup and specimen analysis. Training is also available for investigators wishing to work independently.
The Molecular Imaging Agent Laboratory, led by Dr. Michael Tweedle, pursues problems in cancer diagnosis and therapy using biochemical in vivo imaging. The goal is hyper-effective cancer therapy through biochemically personalized treatment.
The MCIC is a shared technology laboratory located at the Ohio State University, Ohio Agricultural Research and Development Center (OARDC) in Wooster (OH). We house equipment and provide services in microscopy (light, confocal, transmission and scanning electron microscopy), and in the area of genomics and molecular biology (small scale sequencing, genotyping, massive parallel sequencing). Our mission is to support research at the Ohio State University. The facility is also available to other research and educational institutions.
This Core subsidizes the production of transgenic and knockout mice for qualified Core users. The transgenic animal facility (see link) is located in the Biomedical Research Tower.
1) Generation of transgenic mice
2) Knockout mice
4) Assisted Reproduction
Provides assessment of skeletal muscle contractile function
Provides training in assessment of muscle contractile function
Consults on other striated musclefunction, including diaphragm and cardiac muscle function
Provides various contraction protocols, including twitch contraction, tetanic contractions, eccentric contractions, and fatigue experiments.
Biological research museums have a mission similar to that of libraries, but instead of preserving books, biological collections preserve individual organisms. Collections grow continuously through activities of faculty, students, and other researchers, as well as by exchange with other museums. As they grow, collections increase in value, preserving samples of natural variation, documenting the occurrence of species in space and time, and providing a critical basis for our understanding of species identity. Biological collections are also the source of information regarding phylogenetic (evolutionary) relationships, whether morphological or genetic. Without this phylogenetic context, no comparative biology would be possible. We do not have public displays, but focus on research and education.
NanoSystems Laboratory (NSL) provides users with access to advanced material characterization and fabrication tools for research and development applications. NSL operates a diverse set of research instrumentation and research capabilities including Focused Ion Beam/Scanning Electron Microscopy, X-ray diffractometry, SQUID magnetometry, Atomic Force/Magnetic Force microscopy, EDS X-ray microanalysis, e-beam lithography, Electron Spin Resonance spectroscopy, Physical Vapor material deposition, ion milling, ICP/RIE etching, maskless photolithography, Low-Temperature/ High Magnetic field magnetotransport measurements, diamond CVD growth, Kerr microscopy and magneto-optical material studies. NSL also operates two 1,100-square-foot clean room facilities. One clean room houses instruments for material deposition and processing for photo/e-beam lithography, while the other clean room is devoted to processing organic spintronic devices, and other air and moisture sensitive materials. It is equipped with four interconnected gloveboxes with Ar and N₂ atmosphere.
At Nanotech West Lab, we're passionate about micro- and nanotechnology and the potential to transform both research and industry applications. Current research programs at Ohio State span the fields of electronics, optics, advanced materials and characterization, energy, biology and medicine. If you have research to conduct, a market to conquer, or a product you'd like to evolve, Nanotech West Lab is the place to make it happen.
The mission of the new NSF-funded National Gateway Ultrahigh Field NMR Center is to promote and advance cutting-edge science using ultrahigh magnetic fields with focus on the areas of biomolecules and metabolomics by solution and solid-state NMR and materials science.
The centerpiece is a new 1.2 GHz NMR spectrometer with existing shared CCIC high-field NMR systems serving as staging instruments. Commissioning is expected over the next couple of years. Users from Academia, National Research Labs and Industry are supported by expert research scientists at the Center. The Center will also coordinate a diverse range of educational and outreach activities.
At Nationwide Children's Hospital, our vision remains unchanged. We aspire to create the best outcomes for children everywhere. This means families come to Nationwide Children's from around the globe knowing they will get the highest quality care. When your child needs a hospital, everything matters.
The Resource for Native Mass Spectrometry Guided Structural Biology (nMS→SB) was established in 2018 with a 6.8M P41 grant from the NIH National Institute of General Medical Sciences. As a national Biomedical Technology Research Resource, our purpose is to develop and disseminate novel technologies throughout the broader biomedical research community. Our mission is to develop improved native MS as a routine tool and disseminate the technology to the biomedical research community through vendor partnerships and training. The Resource will work with investigators across the nation and globe on challenging biomedical projects ranging from viral hemorrhagic fevers and HIV to cataract formation and neurological disorders.
Click on the Native Mass Spectrometry Guided Structural Biology Collection to see resources utilized by the Native Mass Spectrometry Guided Structural Biology Center. Please note that some Native Mass Spectrometry Guided Structural Biology resources are also utilized by the Wysocki Research Group. To see those resources click on that respective collection.
The objectives of the research group are as follows: Proposing new designs for high performance network-based computing systems by taking advantages of modern networking technologies and computing systems; Developing better middleware, API, and programming environments so that modern network-based computing applications can be developed and implemented in a scalable and high performance manner; Performing the above research in an integrated manner (by taking systems, networking, and applications into account); and Focusing on experimental computer science research.
Welcome to The Ohio State Neuromuscular Biomechanics Lab! Our goal is to provide a scientific basis for the treatment of human movement disorders. To reach this goal, we apply mechanical engineering principles to clinical problems to study musculoskeletal mechanics, design medical devices and procedures, and seek to optimize the functional outcome of clinical and surgical interventions.
The CBC NMR & EPR facility services The Ohio State University by offering user training and access to NMR and EPR spectrometers with various capabilities and features. This facility houses six solution-state NMR spectrometers, one solid-state NMR spectrometer, and one EPR spectrometer. All are available for use by trained users or in coordination with the NMR staff.
The OSU-NRL is used for a wide range of nuclear-related research endeavors, including evaluation of material elemental constituents using neutron activation analysis (NAA) and neutron depth profiling (NDP); evaluation of radiation damage to electronic components and other materials, such as optical fibers and optical fiber-based sensors; evaluation of neutron and gamma-ray radiation sensitive detector performance; isotope production; and biomedical experiments. The OSU-NRL staff provides a variety of instructional services ranging from general tours to group laboratory sessions, and facilitates research projects structured to student and faculty interests.
The OSU-NRL features The Ohio State University Research Reactor (OSURR), as well as a professional gamma-ray spectroscopy system and two gamma-ray irradiators. The OSURR is a pool‑type reactor, with multiple beam ports and dry tubes as irradiation facilities, that is utilized for a variety of instructional, research, and service activities. It is licensed to operate at thermal powers up to a maximum of 500 kilowatts, and at this maximum steady‑state power, the maximum thermal neutron flux in the central irradiation facility is approximately 1.4x1013 n/cm2/s. For current facility use rates, please email firstname.lastname@example.org
The Nutrient and Phytochemical Analytics Shared Resource (NPASR) provides investigators with expert bioanalytical method development and quantitative analysis. This resource supports development of methods and techniques to quantitatively determine nutrients and phytochemicals in foods. It also identifies these compounds and their metabolites in biological samples from human clinical trials and animal model investigations.
NPASR personnel are specialists in analytical chemistry who concentrate their expertise in examining the bioavailability, metabolism and physiological significance of carotenoids, isothiocyanates, isoflavones and other phytochemicals found in many foods.
With authority delegated by the Board of Trustees and under the president, the executive vice president and provost at The Ohio State University has responsibility for the administration, coordination, and development of all academic functions of the university.
The Ohio State University’s research and creative expression community is committed to defining and addressing the world’s most pressing challenges though the creation and dissemination of new knowledge. The Office of Research supports, advances and safeguards these research, scholarly and creative pursuits conducted by our faculty, staff and students. We also provide strategic direction and a unified voice for Ohio State’s research interests locally, nationally and internationally.
OARDC is a premier institution committed to safe, healthy, and affordable food and agricultural products; sustainable food and agricultural systems; strong rural and urban communities; stewardship of natural resources and the environment; keeping Ohio positioned favorably in a global economy.
Our mission is to improve the economic condition of rural areas in Ohio and West Virginia through the development of all types of cooperative businesses and "cooperative like" groups. OCDC is a part of a business development, research, and extension education team at the Ohio State University South Centers, allowing the center to effectively provide comprehensive resources for new and emerging cooperatives in Ohio and West Virginia.
The Ohio Supercomputer Center empowers a wide array of groundbreaking innovation and economic development activities in the fields of bioscience, advanced materials, data exploitation and other areas of state focus by providing a powerful high performance computing, research and educational cyberinfrastructure for a diverse statewide/regional constituency.
The Ohio Supercomputer Center partners strategically with Ohio researchers — especially following the 2002 establishment of a focused research support program — in developing competitive, collaborative proposals to regional, national, and international funding organizations to solve some of the world's most challenging scientific and engineering problems.
The Ohio Supercomputer Center leads strategic research activities of vital interest to the State of Ohio, the nation and the world community, leveraging the exceptional skills and knowledge of an in-house research staff specializing in the fields of supercomputing, computational science, data management, biomedical applications and a host of emerging disciplines.
Under the guidance of the research program director, residents develop a research project and are expected to present their research at the meeting (AAO, IADR, AADR etc.,). Residents are also required to publish their manuscript to a refereed journal by graduation. This process promotes creative thinking, critical analysis, and teaches residents to recognize the importance of evidence-based knowledge. Residences are provided with experience in biomedical sciences, scientific methodology, and research techniques so they may develop an appreciation for the biological and scientific aspects of orthodontics.
Weiqiang (John) Zhao, MD, PhD, FCAP serves as the director of the PCF. The lab is a CLIA approved, CAP certified laboratory performing many basic and advanced services. Five laboratories comprise the Pathology Core Facility (PCF) including histology, fluorescent (FISH)/in situ hybridization (ISH), immunohistochemistry (IHC), molecular, and research and development. The PCF provides a wide array of histology based research and clinical services with qualified, well-trained clinical technologists and research assistants maintaining a cohesive and seamless infrastructure ensuring consistent results and quick turn around times.
Aside from functioning as a histology based research service to investigators, the PCF provides laboratory services to the ALLIANCE for Clinical Trials and Oncology which is one of the multidisciplinary cooperative cancer treatment groups funded by the National Cancer Institute (NCI), a division of the National Institutes of Health (NIH). The PCF’s role in this group is to prepare stained and unstained tissue sections, isolate nucleic acids (DNA and RNA) from paraffin embedded tissue samples as well as construct tissue microarrays for further testing and data collection. The goal of this program is to seek improved methods of cancer therapy and prevention.
The laboratory also serves as the tissue repository for the Adenoma Polyp Tissue Bank (APTB) national clinical cancer treatment group, whose focus is to study the efficacy and safety of the drug celecoxib in preventing the occurrence of new adenomatous polyps, which put people at increased risk for colorectal cancers.
The Plant and Animal Agrosecurity Research (PAAR) facility is a highly secure biocontainment building. It is required by federal law for conducting research with organisms that cause diseases in animals classified at biosafety level 3 (BSL-3 and/or BSL-3 Ag). It is also needed for working with plant diseases that could cause undue economic hardship on agriculture if released into the environment.
PAAR is the only facility in Ohio and one of only three nationally with mission for both plant and animal research at the BSL-3 and BSL-3 Ag safety levels. Another three facilities nationwide have the BSL-3 Ag safety level designation for animal-related research only. The Ohio State University has a BSL-3 labs on its Columbus campus, but PAAR is the first BSL-3 facility on the Wooster campus and the university’s first BSL-3 Ag facility.
PAAR enhances OARDC’s nationally and internationally recognized research programs on infectious diseases of plants and animals — further contributing to the viability of Ohio’s $90-plus billion agricultural sector, the state’s largest industry. The facility will allow Ohio to proactively develop new diagnostic tools, treatments, vaccines to reduce economic losses from diseases and pests. It enhances OARDC’s ability to attract highly competitive faculty and grants to the state.
27,537 gross square feet.
Two BSL-3 enhanced laboratories and four BSL-3 Ag animal isolation rooms that can handle large animals, such as cows and pigs.
Office, lockers and change facility, decontamination areas, wash areas to clean cages, and a necropsy area for sample collection.
Specialized equipment to work with microorganisms in laboratory settings.
Special airtight construction.
Outgoing air is filtered through High Efficiency Particulate Air (HEPA) filters that trap microorganisms and prevent escape into other sections of the facility and the surrounding environment.
Complies with all federal guidelines governing BSL-3 and BSL-3 Ag labs.
The Facility, established in 2000, serves the entire Ohio State University as well as the researchers in the state of Ohio and beyond, by providing resources in order to study genomes from DNA sequence to protein activities. Despite our name, the Facility can study any organism's DNA, RNA or protein. The Facility provides 5 major services: 1) DNA Sequencing, 2) Genotyping, 3) Gene Promoter Characterization, 4) Real-time PCR, , and 5) Biomolecular Interaction Analysis. The procedures are designed to provide the opportunity to obtain high quality results at a reasonable cost. This is a cost recovery unit while tours and demonstrations for any group or individual are free. Please explore the website and feel free to contact us in order to learn about how we can assist you.
The Byrd Polar and Climate Research Center Archival Program (Polar Archives) advances knowledge, research, and learning about the world’s polar regions by collecting, preserving, and making accessible historical records, personal papers, photographs and other forms of documentation related to the exploration of the world’s polar regions.
The Polar Rock Repository is a national facility constructed adjacent to Scott Hall, home of the Byrd Polar Research Center, The Ohio State University. It is supported by the National Science Foundation's Office of Polar Programs. The repository houses rock samples from Antarctica, the southern oceans, South America and small collections from Africa and Australia. The rock collection and database includes field notes, photos, maps, cores, powder and mineral residues and thin sections. Rock samples may be used for research by university scientists. Samples may also be borrowed for educational or museum use in the United States. Visitors are welcome at the PRR by appointment.
We provide RNA and DNA quality control using the BioRad Experion electrophoresis-on-a-chip system.
GeneChip data often need to be confirmed by single-gene oriented analytical approaches such as real-time PCR. The core is equipped with the ABI 7900HT real-time PCR System as well as Primer Express for primers design.
The RISSR assists investigators with a comprehensive range of services related to research design and the selection and/or development of surveys, and studies measures to appropriately capture targeted constructs.
The Department of Research Information Technology (RIT) advances biomedical research in the health sciences by providing necessary technology and data services, allowing researchers to focus on their research. Our products and services support all aspects of basic, clinical, and translational research. We provide research informatics, data collection via electronic data capture, user experience and design for static and interactive applications, custom software development, data science and engineering, and development of innovative multi-modal solutions to execute transformative research. We support all research lifecycle phases, providing resources and guidance from the proposal phase through closeout and study data retention.
The Center for Nursing Research in the College of Nursing has two wet laboratories located on Newton Hall's lower level. The center also houses two wet laboratories which are staffed by a fulltime research specialist who is available to consult with faculty and students on laboratory methods and to assist with assays as needed. The laboratories are equipped with 3 refrigerated centrifuges, water baths, pH analyzers, microbalances, microscopes, a CO2 incubator and a level III biosafety cabinet for cell culture, an ultrapure water system, 4 refrigerators, one -20 freezer and three -80 freezers. Specialty equipment for analysis of nicotine metabolites includes a Hitachi Liquid Chromatography System with UV detector, a D-7500 Integrator and autosampler, and three Bedfont Mini-Smokerlyzer instruments for noninvasive monitoring of expired air CO than can be easily transported for analyses in outpatient settings.
Equipment for measurement of hormones, cytokines, immunoglobulins, and other bioactive peptides in blood, saliva, urine and cell culture fluids includes power sources for gel electrophoresis, a Gel-Logic Image System for viewing and quantifying band density on western blots and agarose gels, and two microplate readers for ELISA and other chromagen-based assays. Equipment for real-time PCR includes a PCR Workstation, a Nanodrop 2000, and an iCycler and CFX96 thermocycler which are interfaced with a dedicated desktop computer and software for data storage and analysis. Faculty and students also have access to a Meso-Scale Discovery Reader housed in the GCRC for analysis of up to nine different cytokines using a chemiluminescense platform.
The Resource for Native Mass Spectrometry Guided Structural Biology (nMS→SB) was established in 2018 with a 6.8M P41 grant from the NIH National Institute of General Medical Sciences. As a national Biomedical Technology Research Resource, our purpose is to develop and disseminate novel technologies throughout the broader biomedical research community. Our mission is to develop improved native MS as a routine tool and disseminate the technology to the biomedical research community through vendor partnerships and training. The Resource will work with investigators across the nation and globe on challenging biomedical projects ranging from viral hemorrhagic fevers and HIV to cataract formation and neurological disorders.
The Office of the Vice President for Research provides resources and education to the Ohio State research community for the identification of extramural funding opportunities.
One of the most comprehensive funding search tools is infoEd Global SPIN which is available to all faculty, staff, and students. SPIN provides a comprehensive and up-to-date database of grants, fellowships, awards, and other funding opportunities from public, private, domestic, and international sources in every discipline.
Users may create e-mail funding alerts based on key words, i.e., areas of interest, academic disciplines.
The InfoEd SPIN database contains over 40,000 distinct opportunities from more than 10,000 global sponsors. SPIN provides both active searching as well as automated, daily opportunity notifications.
The Rodent Behavior Core is funded in part by an Institutional Core Grant from the National Institutes of Neurological Disorders and Stroke (P30-NS045758). We are conveniently located in the Biomedical Research Tower on Central Campus. The Rodent Behavior Core staff provides scientists with consultation and technical expertise using a standard battery of behavioral testing to identify phenotype of mutant and transgenic rodents.
Founded in December 2012 by a collection of new and energetic Ohio State faculty, postdocs and staff, the STEAM Factory is a diverse and inclusive grass-roots network in the Ohio State community that facilitates creative and interdisciplinary collaboration, innovation and dissemination.
To provide opportunities for collaboration that enhance and drive innovation within all research disciplines;
To provide linkages and interdisciplinary interactions between Ohio State departments and colleges; and
To increase the public awareness, understanding and impact of Ohio State research.
The BPCRC sediment core repository archives marine and lake sediment samples collected from the Arctic Ocean and the Eurasian Arctic margin on the NSF-OPP and ONR-sponsored projects since 1992. The collection was significantly expanded by the addition of cores from the 2005 Healy-Oden Trans-Arctic Expedition (HOTRAX) — the first complete geological-geophysical transect across the central Arctic Ocean. Currently the BPCRC collection contains >600 m of sediment core material. The core information is searchable via the Index to Marine and Lacustrine Geological Samples (IMLGS). Considering the expensiveness of research cruises to the high Arctic, this material and derived data constitute a highly valuable contribution to the infrastructure of the U.S. marine geological and paleoclimatic research.
The Semiconductor Epitaxy and Analysis Laboratory (SEAL) includes the first University Molecular Beam Epitaxy (MBE) facility developed in the state of Ohio (1994) and unique, world-class facilities to grow and characterize nanostructured electronic materials. SEAL’s inception as OSU’s MBE Laboratory came via interdisciplinary funding from OSU’s Center for Materials Research to Professor Ringel and rapidly became the central laboratory around which massive expansion of the electronic materials, optoelectronics and device research areas has occurred.
Facilities for MBE growth of arsenide and phosphide based III-V compound semiconductors, epitaxial metallic multilayers, and SiGe, along with an array of sophisticated in-situ characterization tools, including x-ray photoelectron spectroscopy (XPS), Auger electron spectroscopy (AES), and scanning tunneling microscopy, are linked along a common ultra-high-vacuum transfer assembly so that flexibly in-situ sample transfer between all deposition and characterization chambers is feasible. The ability to transfer between epitaxy chambers and atomic-scale and chemically-sensitive characterization tools within a UHV environment, coupled with the wide range of materials being studied III-V compounds based on (Al,In,Ga)/(As,P), IV-IV semiconductors, magnetic and nonmagnetic metallic layers make this a unique facility for leading edge research in electronic materials, heterostructures and nanostructures.
SEAL incorporates major facilities obtained with equipment grants to EMDL and also to EMDL’s collaborators from the College of Engineering, Department of Physics and the Center for Materials Research who have contributed capabilities to the SEAL UHV cluster. Hence, the interdisciplinary nature of the Laboratory, which is at the core of its formation, translates into close collaborations between engineers, physicists, and industrial partners, providing unique research opportunities for students and senior researchers throughout the colleges of Engineering and Math & Physical Sciences.
Several laboratories have been established at Ohio State to support the development of solid-state sensors. These facilities and accompanying capabilities, along with those in the Center for Industrial Sensors and Measurements (CISM), include:
Thick-film and thin-film fabrication devices
Electronic nose along with artificial intelligence and neural-net software
A wide range of electrical measuring equipment
A complete sensor measurement and testing facility with the capability for controlled gas flow and mixing systems
Computer-controlled data acquisition and analyses
The Small Animal Imaging Core (SAIC) is a small-animal imaging facility available to all investigators and other academic and commercial institutions.
The SAIC houses high-resolution imaging equipment and offers assistance from professionals who are experts in operating each imaging modality, small animal handling, and analytical software support for quantitative image analysis.
The goal of the Small Animal Metabolic Core is to provide expertise in metabolic studies including whole body metabolism, food intake and physical activity in small rodents.
The mission of the Small Animal Research Imaging Core (SARIC) is to provide non-invasive, whole animal imaging of rodents used in preclinical research studies at The Ohio State University.
The Solid Tumor Translational Science Shared Resource (STTSSR) team works closely with clinical and translational scientists to develop a customizable portfolio of biomarker assays in order to provide innovative, correlative science studies associated with early-phase solid tumor oncology clinical trials. This resource works closely with clinical investigators in the design and management of studies and provides guidance related to assay development and analysis. The STTSSR serves as a central repository for specimens collected from patients on trials and is responsible for processing the tissue for any number of downstream analyses. In addition to developing novel assays, i the STTS-SR partners with other OSUCCC Shared Resources to utilize available technologies such as next-generation sequencing, RNA expression analysis and proteomics. In these situations, the STTSSR is responsible for obtaining and preparing the patient samples for downstream analyses and then collects and organizes the data.
The STTSSR resource also helps identify and develop partnerships among investigators and pharmaceutical companies to gain access to new drugs and compounds and to provide corresponding correlative testing and analyses for cancer studies.
All samples received within the HTRN Specialty Lab are accessioned and processed based on the research protocol requirements. Services include blood sample processing into different subtypes (plasma, buffy coat and serum), nucleic acid extraction from blood and tissue, and various sample banking, pulling and distribution. Also, special leukemia cell differential staining and cell counting can be provided upon request.
Our mission at the Spine Research Institute is to systematically improve the way we prevent, evaluate, and treat spine disorders through the identification of disorder causal pathways. We accomplish this mission through collaborative research, education, and the development of platform technologies.
OSU Sports Medicine offers the largest team and the most comprehensive interdisciplinary approach to the prevention and treatment of injuries in athletes and active individuals.
Our pursuit of excellence in research, patient care and education is enhanced by our position within a nationally prominent academic medical center, which allows the integration of strengths from many specialties.
Our team of experts provides personalized care in sports medicine, sports performance, orthopaedics, rehabilitation, nutrition, concussion management and sport psychology.
Introducing the State Climate Office of Ohio (SCOO)
Accessing accurate climate information, education, and interpretation is critical for policy makers and all sectors of Ohio’s economy and will enhance the quality of life, health, food and water security, and economic prosperity of all Ohioans. The State Climate Office of Ohio (SCOO) is a new team based at The Ohio State University (OSU) that connects Ohioans with transformative climate information.
The SCOO Prospectus
SCOO embodies four core mission activities focused on connecting people and climate: Communication, Information Services, Education & Outreach, and Research. We have already forged many partnerships that should yield positive impacts with regard to climate-related engagement and communication, including connections with OSU Extension in the College of Food, Agriculture, and Environmental Science (CFAES) and its associated instrumental observation network, the Ohio Agricultural Research and Development Center (OARDC) Weather Network; the Ohio Emergency Management Agency (OEMA); and the Midwest Regional Climate Center (MRCC).
Key climate-related questions require engagement of experts from many disciplines, sectors (energy, security, food, health), and institutions, underlain and sustained by transformative data stewardship that facilitates a climate aware and resilient society. How will Ohio adapt and build resilience to a warmer world? What will be the imprint of climate variability on our economy, food security, natural resources, energy infrastructure, health and well-being? What are the chances and potential manifestations of extreme floods and droughts? How can Ohioans build resilience to actual and future climate disruptions?
Ohio Sea Grant research focuses on critical issues facing Lake Erie, from harmful algal blooms and invasive species to climate change and economic development. Collaborations with a wide range of partners ensure that research is relevant and applicable to current problems and concerns, and a summer research program for undergraduate science majors ensures that the next generation of Lake Erie scientists is well prepared for anything the future may throw at them.
The Surface Analysis Laboratory (SAL) provides access to high end X-ray photoelectron spectroscopy (XPS) instrumentation. The facility is equipped with a traditional UHV characterization XPS and a high end near ambient pressure XPS for in-situ analysis of samples in the presence of a gas phase of interest.
The Target Validation Shared Resource (TVSR) assists investigators in generating reliable proof-of-concept preclinical animal model data for grant applications, publications and IND applications for the FDA.
Preclinical mouse models of cancer have become indispensable for in vivo target validation studies, such as determining in vivo efficacy of therapeutics, unraveling in vivo off-target effects of therapeutics including unexpected negative side-effects in a whole organism, elucidating significance of biological pathways towards disease initiation/progression etc. The Target Validation Shared Resource assists investigators with these in vivo target validation studies.
The TVSR shared resource has expertise in establishing breeding programs for GEMM (genetically engineered mouse model) animals and immune-compromised mouse strains, developing xenograft/allograft mouse models of cancer, therapeutic compound administration and subsequent monitoring of the animals. It also provides consultation towards in vivo target validation study design.
The goal of TVSR is to assist investigators in generating reliable “proof-of-concept” preclinical animal (mouse) model data for grant applications, publications and filing of IND applications to FDA.
The Agroecosystem Management Program (AMP) at the Ohio State University supports educational offerings in sustainable agriculture, facilitates regional collaboration and coordinates agroecosystems research to develop a food economy in Ohio that is environmentally friendly, socially responsible and economically sustainable – from farm to consumer.
The Proteomics Shared Resource (PSR) provides OSUCCC – James members with complete proteomic support using a wide range of state-of-the-art mass spectrometers based analytical platforms. The PSR offers extensive technical expertise, leading mass spectrometers and supporting equipment to identify and characterize proteins, protein complex (via Native MS analysis), protein modifications, protein interactions and protein biomarkers as well as protein quantitation studies in cancer samples from various sources such as serum, urine, BAL fluid, saliva, frozen tissues, cell culture media, formalin-fixed tissues and cell lysates. The PSR also provides qualitative/statistical downstream analysis and visualization of data.
The approach taken by OSU Center for Pharmacogenomics (C-PGx) spans across basic biomedical sciences and functional genomics to clinical implementation. In addition, the C-PGx educates academic and industrial scientists, health-care professionals, and the public, about the potential of pharmacogenomics in medical practice. The C-PGx focuses on the discovery of genetic variants that serve as biomarkers guiding successful drug therapy in individual patients. C-PGx has developed new approaches for the discovery of genetic variants, with focus on gene regulation, including innovative genome-scale technologies such as massively-parallel sequencing and data integration. Together with numerous collaborators across the world, C-PGx scientists have already generated clinically relevant biomarkers guiding optimal therapies for the individual patient.
The Environmental and Social Sustainability (ESS) Lab is a hub of sustainability research at The Ohio State University. Led by academic faculty and supported by a professional research staff, the ESS Lab provides policy and marketing insight to partners through professionally managed surveys, behavioral research, and targeted behavioral interventions related to environmental and social sustainability.
Welcome to the Fontana Corrosion Center in the Department of Materials Science and Engineering at The Ohio State University.
Home to one of world's richest traditions in corrosion research, with activities focused on aqueous corrosion, environmental fracture, high-temperature corrosion, oxidation, and modeling.
The Genome Editing Shared Resource (GEdSR) provides support to investigators in the design and establishment of gene-editing approaches for their experimental needs. By using CRISPR/Cas9-based technologies, the GEdSR helps research groups in the generation of knock-out and knock-in cellular systems. The GEdSR has 2 different sites of operation, located at the James Comprehensive Cancer Center and the Nationwide Children’s Hospital. The two sites have the capability to support both basic and translational gene-editing approaches.
The Infant Laboratory team explores infant development, assessing babies' physical (motor) and mental (cognitive) skills. The Infant Lab’s research looks at babies who are reaching their developmental milestones on schedule and those who are delayed. The goal is to develop techniques to identify developmental delays sooner and early intervention programs that will help infants with delays catch up.
The Knowledge Bank is a collaborative service of the Ohio State University Libraries and the Office of the Chief Information Officer. Faculty, staff and graduate students associated with the Ohio State University are invited to deposit digital materials for long-term preservation and world-wide electronic accessibility. OSU communities are invited to use the Knowledge Bank to distribute their intellectual output. Examples of communities are academic departments, administrative units, programs, and interdisciplinary centers. Types of content include working papers, post prints, annual reports, technical reports, proceedings of conferences, senior honors theses, digital stories, interviews, videos, images, books, newsletters and journals.
The Microscopy Shared Resource (MSR) provides timely and high-quality services to support OSUCCC investigators with instrumentation, technical advice and training on a variety of sophisticated microscopy approaches, including detection of viruses; examination of nanostructures for drug delivery with transmission electron microscopy; live cell imaging in response to different treatments; reconstruction of tumor models in three dimensions; and following dynamic events, such as the movement of immune cells in tumors of living animals using multiphoton microscopy. The MSR provides two critical shared resources, CEMAS and CMIF, for cancer investigators to translate fundamental studies of cancer biology into new treatments.
The OBIC Bioproducts Innovation Center (OBIC), located at The Ohio State University, connects different segments of the bioproducts community to nurture business ecosystems and facilitate commercialization of new sustainable bioproduct technologies.
OBIC's internal staff, as well as a network of consultants, seeks to provide a series of services. We work with many different groups with varied interests to accomplish shared goals.
The Pharmacogenomics Core Lab in the OSU Center for Pharmacogenomics offers state of the art Next Generation Sequencing. We are an Ion Torrent Certified Service Provider for AmpliSeq transcriptomes and exomes as well as whole transcriptome analysis.
The OSUCCC – James is one of only 41 comprehensive cancer centers in the nation as designated by the National Cancer Institute (NCI), a designation that we have maintained through competitive renewal since 1976. After the site review for our most recent renewal, we earned the NCI's highest ranking, "exceptional.” The NCI survey team stated that the OSUCCC – James "should serve as the model for other matrix university-based centers."
The OSUCCC – James has 20 shared resources and core facilities that provide specialized services to cancer researchers. They offer cost-effective, state-of-the-art technology and instrumentation; expert guidance and training; and clinical, administrative and technical support.
The Pharmacoanalytic Shared Resource (PhASR) supports pre-clinical and clinical drug development at Ohio State by providing high quality and cost-effective bioanalytical method development, quantitative sample analysis, and pharmacokinetic / pharmacodynamic experimental design, data analysis and modeling.
Expertise among PhASR personnel includes quantitative pharmacology; bioanalytical methodology, design and conduct of pharmacokinetic/pharmacodynamic studies in animal disease models and in humans enrolled in clinical trials; data analysis and modeling of PK/PD data to inform drug development decisions. PhASR personnel are available for consultation on clinical or pre-clinical PK/PD experimental design and analysis.
Our mission is to provide food industry companies, the Department of Food Science and Technology, and related institutions with technical and scientific services through education, research, and product development with highly skilled personnel, a fully equipped pilot plant, and teaching facilities.
The Tissue Bank (Biospecimen Repository) collects samples of tumors and normal tissue from dogs and cats, and stores these tissues under controlled conditions for future use by multiple investigators. The Tissue Bank at The Ohio State University was selected by the Canine Comparative Oncology Genomics Consortium (CCOGC) as one of three veterinary institutions nationwide to participate in populating the Pfizer-CCOGC multi-institutional Tissue Bank. this National Cancer Institute-sponsored endeavor emphasizes the importance of comparative oncology research. The Tissue Bank at The Ohio State University follows the guidelines established by the CCoGC for several specific types of tumors and similar established protocols for other tumors. Tissues are collected and archived only after receiving consent from the owners. This sample bank will serve as a tremendous resource with the ultimate goal fo developing new prevention and treatment strategies for dogs with a variety of illnesses.
The Trace Element Research Laboratory (TERL) has world-class capabilities for elemental chemical measurements for an incredibly wide variety of applications in earth, environmental, chemical, biological, medical and materials sciences. Superb expertise and state of the art inductively coupled plasma based optical emission and mass spectrometry instruments are available. Most of the elements in the periodic table (other than C, N, O, F and noble gas elements) can be measured at concentrations from major (%) to ultratrace (part per trillion). Measurements can be made on solution samples, solids following digestion or, using laser ablation sampling, directly on solids.
The TERL provides facilities and expertise to researchers, students and faculty throughout The Ohio State University in variety of ways. Properly trained researchers, students and faculty can use the facilities independently or in collaboration with our staff. On the other extreme, TERL staff discuss research or analyses problems of interest with faculty, students or clients, design the appropriate measurements, make the measurements and provide analysis results.
Our mission includes teaching of the fundamental concepts and practical measurement techniques through traditional courses, short courses and one-on-one sessions. The TERL encourages faculty to use the facilities and staff expertise in their teaching activities.
We also provide services and expertise to other Universities, government organizations, individuals and industry at rates on a par with commercial laboratories with a special emphasis on unique method development and problem solving.
Ohio State’s Translational Data Analytics Institute is a regional hub for team science and workforce development in data science and analytics, thanks in part to a significant investment by the state of Ohio. Our faculty, who represent more than 50 different academic disciplines, work with industry and community partners to educate and train tomorrow’s workforce and create data-enriched solutions for societal challenges such as opioid addiction, climate-resilient agriculture and infant mortality.
University Laboratory Animal Resources (ULAR) facilitates the humane care and use of animals in biomedical research and teaching at Ohio State and also provides veterinary services. ULAR staff members oversee compliance with federal regulations and guidelines related to animal use and promote the responsible use of animals for the benefit of society.
University Libraries provides patrons with access to information at 15 locations across the Columbus campus, through the web site, library.osu.edu, and by phone, 614-292-OSUL (6785).
The Veterinary Biospecimen Repository collects both tumor and normal (whole blood, tissue, serum, plasma, urine) samples following guidelines modeled after the Children’s Oncology Group tissue banking protocols and serves as a valuable resource of spontaneous tumors in the pet population with the goal of characterizing these tumors to provide a framework for evaluation of novel therapeutic approaches in animals and humans. The VCRS is a unique shared resource enabling the integration of multiple models of cancer into the process of drug development and translational therapeutics.
The Veterinary Clinical Research Support Shared Resource (VCRSSR) designs and conducts clinical trials in companion animals with spontaneous diseases to evaluate novel diagnostics and therapeutics and collects biospecimens, such as tissue biopsies, serum, plasma and urine, in support of comparative cancer research. The overriding goal of this resource is to advance the diagnosis and treatment of disease in veterinary patients while enhancing the health of humans through comparative and translational studies.
Under the direction of Vicki Wysocki, Professor of Chemistry and Biochemistry, Ohio Eminent Scholar, Director of the Campus Chemical Instrument Center, and Director of the NIH-funded Resource for Native Mass Spectrometry Guided Structural Biology, the Wysocki group includes graduate and undergraduate students, postdoctoral researchers and research staff,. Research in the Wysocki group is categorized into four broad areas: (1) development and implementation of surface-induced dissociation onto commercial time-of-flight, Orbitrap and FT-ICR instruments, (2) development and application of native mass spectrometry-guided structural biology approaches, (3) multi-omics approaches to biomarker discovery, disease diagnosis and prognosis using proteomics and metabolomics methods coupled with genomics and transcriptomics, and (4) determination of peptide and other fragment ion structures by IR action spectroscopy.
Single crystal X-Ray diffraction is a leading technique for the determination of molecular and crystal structures and for obtaining the absolute configuration of molecules. This laboratory allows researchers to do small molecule single crystal structure determinations, where the metrical details of a molecule are ascertained (such as, bond lengths, bond angles, and conformation) along with the arrangement of the molecules within the solid state. Students with crystallographic experience can collect diffraction data and/or solve and refine their own structures. Otherwise, the complete structure analysis is done by the staff crystallographer
The purpose of the Xenograft Core is to bring together investigators studying brain cancer (glioblastoma) biology and novel therapeutics to combat these cancers. The chief purpose of the Core will be to facilitate the analysis of brain tumors in animal models by providing the facilities and technical expertise to conduct these experiments. The Core will allow common experimental approaches to be centralized and a trained technician to perform the common experiments.
Tumor cell implantation in rodents: Subcutaneous and orthotopic.
Tumor volume measurements
Follow up of Rodent Survival
Euthanasia and Tissue harvest
The facility contains 1,300 tanks of various sizes, and areas for experimentation, food production, cleaning and storage. Aquaculture systems support rearing of zebrafish from fertilized embryos to adults. The facility currently houses numerous wildtype lines and dozens of mutant and transgenic lines. A separate system for the importation of zebrafish lines from universities worldwide is also located in the facility. All phases of zebrafish husbandry are carried out by Zebrafish facility staff and members of the Henion, Beattie and Jontes labs. NIH grant P30- NS045758 partially funded a major expansion of the facility.
The Zebrafish Genetics Core provides expertise and support for targeted gene disruption and subsequent generation of mutant zebrafish. The engineered Zn-finger nuclease approach is also amenable to other model systems. In addition, the Core provides services for BAC engineering leading to the production of transgenic zebrafish or for use in other model systems.
Found 209 resource providers .